PMID- 21981846
OWN - NLM
STAT- MEDLINE
DCOM- 20120301
LR  - 20111108
IS  - 1769-6623 (Electronic)
IS  - 0750-7658 (Linking)
VI  - 30
IP  - 11
DP  - 2011 Nov
TI  - [Proton pump inhibitors: impact of professional practice evaluation on 
      prescriptions pertinence].
PG  - 814-8
LID - 10.1016/j.annfar.2011.07.004 [doi]
AB  - OBJECTIVE: To improve the quality of proton pump inhibitors (PPI) prescription in 
      an orthopaedic department. STUDY DESIGN: Prospective professional practice 
      evaluation study. PATIENTS AND METHODS: A specific protocol concerning the best 
      practice for using PPI in the perioperative period was established by 
      anaesthesiologists and validated by all prescribers, according to recent 
      recommendations published by French Afssaps. PPI prescription pertinence, mainly 
      using the oral route, was based upon the presence of clearly identified risk 
      factors. PPI mensual consumption and severe gastric complications were analyzed 
      and compared with those obtained from the previous year. Ten months after the 
      beginning of the protocol, the pertinence of PPI prescription was analyzed in 20 
      randomly selected medical records. Data are expressed in defined daily dose 
      (DDD). RESULTS: After one year, a 35.5% decrease in oral PPI consumption was 
      noted (901 +/- 211 before vs 581 +/- 235 DDD, after, P<0.05). A similar trend to a 
      decrease in intravenous PPI consumption was observed (40 +/- 23 vs 22 +/- 26, 
      P=0.06). During the same period, the overall incidence of severe gastric 
      complication remained stable. The PPI prescription was pertinent in 85% of 
      selected medical records. CONCLUSION: This study confirmed the interest of 
      professional practice evaluation protocols to improve PPI prescription. A strong 
      implication of all medical staff members is mandatory to maintain such benefits 
      over time.
CI  - Copyright (c) 2011 Elsevier Masson SAS. All rights reserved.
FAU - Fuzier, R
AU  - Fuzier R
AD  - Service orthopedie, pole anesthesie-reanimation, faculte de medecine, CHU Purpan, 
      universite Toulouse-III, place Dr.-Baylac, TSA40031, 31059 Toulouse cedex 9, 
      France. fuzier.r@gmail.com
FAU - Magues, J-P
AU  - Magues JP
FAU - Dupuis, E
AU  - Dupuis E
FAU - Pomies, S
AU  - Pomies S
FAU - Segui, S
AU  - Segui S
FAU - Senard, J-M
AU  - Senard JM
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - Inhibiteurs de la pompe a protons : impact d'une evaluation des pratiques 
      professionnelles sur la pertinence des prescriptions.
DEP - 20111005
PL  - France
TA  - Ann Fr Anesth Reanim
JT  - Annales francaises d'anesthesie et de reanimation
JID - 8213275
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Anesthesiology/trends
MH  - Drug Prescriptions/*statistics & numerical data
MH  - Drug Utilization
MH  - France
MH  - Gastrointestinal Diseases/prevention & control
MH  - Humans
MH  - Practice Guidelines as Topic
MH  - Professional Practice
MH  - Prospective Studies
MH  - Proton Pump Inhibitors/administration & dosage/adverse effects/*therapeutic use
EDAT- 2011/10/11 06:00
MHDA- 2012/03/02 06:00
CRDT- 2011/10/11 06:00
PHST- 2010/11/16 00:00 [received]
PHST- 2011/07/19 00:00 [accepted]
PHST- 2011/10/11 06:00 [entrez]
PHST- 2011/10/11 06:00 [pubmed]
PHST- 2012/03/02 06:00 [medline]
AID - S0750-7658(11)00291-7 [pii]
AID - 10.1016/j.annfar.2011.07.004 [doi]
PST - ppublish
SO  - Ann Fr Anesth Reanim. 2011 Nov;30(11):814-8. doi: 10.1016/j.annfar.2011.07.004. 
      Epub 2011 Oct 5.