PMID- 21987055 OWN - NLM STAT- MEDLINE DCOM- 20120123 LR - 20161021 IS - 1934-3647 (Electronic) IS - 1934-3647 (Linking) VI - Chapter 19 DP - 2011 Oct TI - Phylogenetic analysis of protein sequence data using the Randomized Axelerated Maximum Likelihood (RAXML) Program. PG - Unit19.11 LID - 10.1002/0471142727.mb1911s96 [doi] AB - Phylogenetic analysis is the study of evolutionary relationships among molecules, phenotypes, and organisms. In the context of protein sequence data, phylogenetic analysis is one of the cornerstones of comparative sequence analysis and has many applications in the study of protein evolution and function. This unit provides a brief review of the principles of phylogenetic analysis and describes several different standard phylogenetic analyses of protein sequence data using the RAXML (Randomized Axelerated Maximum Likelihood) Program. CI - (c) 2011 by John Wiley & Sons, Inc. FAU - Rokas, Antonis AU - Rokas A AD - Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA. LA - eng PT - Journal Article PL - United States TA - Curr Protoc Mol Biol JT - Current protocols in molecular biology JID - 8908160 RN - 0 (Proteins) SB - IM MH - Cluster Analysis MH - Computational Biology/*methods MH - Likelihood Functions MH - *Phylogeny MH - Proteins/*classification/*genetics MH - *Sequence Homology, Amino Acid EDAT- 2011/10/12 06:00 MHDA- 2012/01/24 06:00 CRDT- 2011/10/12 06:00 PHST- 2011/10/12 06:00 [entrez] PHST- 2011/10/12 06:00 [pubmed] PHST- 2012/01/24 06:00 [medline] AID - 10.1002/0471142727.mb1911s96 [doi] PST - ppublish SO - Curr Protoc Mol Biol. 2011 Oct;Chapter 19:Unit19.11. doi: 10.1002/0471142727.mb1911s96.