PMID- 21988274 OWN - NLM STAT- MEDLINE DCOM- 20120502 LR - 20221207 IS - 1557-8593 (Electronic) IS - 1520-9156 (Linking) VI - 14 IP - 1 DP - 2012 Jan TI - ROSSO-in-praxi follow-up: long-term effects of self-monitoring of blood glucose on weight, hemoglobin A1c, and quality of life in patients with type 2 diabetes mellitus. PG - 59-64 LID - 10.1089/dia.2011.0116 [doi] AB - BACKGROUND: Self-monitoring of blood glucose (SMBG) is a simple tool to monitor the effects of lifestyle change on blood glucose. Recently, the ROSSO-in-praxi Study demonstrated that addition of SMBG to a 12-week lifestyle intervention was associated with significant improvements in glucometabolic control and quality of life in insulin-naive patients with type 2 diabetes mellitus (T2DM). So far it is unknown if this short-term intervention also has long-term effects. Therefore, participants were followed up for a mean period of 2 years. METHODS: Participants (n=327) were asked by mail for current weight, hemoglobin A1c (HbA1c), performance of SMBG, and quality of life (SF36 and CES-D questionnaires). Participants who did not reply were contacted by phone. RESULTS: Two hundred twenty-eight participants (70%) completed the follow-up. During the 12-week lifestyle intervention they had significantly reduced weight (2.2 kg) and HbA1c (0.3%; P<0.001 each). After 2 years they achieved a further reduction of weight (0.2 kg; P<0.001), whereas HbA1c increased again, remaining 0.1% lower than baseline. The numbers of depressed participants remained stable during follow-up, whereas physical and mental health-related quality of life remained better compared with baseline. During follow-up 20% of participants continued SMBG daily, 35% several times a week, and 33% irregularly. It is interesting that participants with daily SMBG demonstrated an HbA1c decrease of 0.3% at time of follow-up, whereas in those who stopped SMBG HbA1c increased by 0.1% (P=0.05). CONCLUSIONS: Integration of a short-term, motivational, and low-cost intervention into basic therapy of T2DM has had beneficial long-term effects on weight and quality of life and, if SMBG was continued daily, also on HbA1c. FAU - Kempf, Kerstin AU - Kempf K AD - West-German Centre of Diabetes and Health, Dusseldorf Catholic Hospital Group, Dusseldorf, Germany. kerstin.kempf@wdgz.de FAU - Kruse, Johannes AU - Kruse J FAU - Martin, Stephan AU - Martin S LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20111011 PL - United States TA - Diabetes Technol Ther JT - Diabetes technology & therapeutics JID - 100889084 RN - 0 (Glycated Hemoglobin A) SB - IM MH - *Blood Glucose Self-Monitoring/methods MH - Body Weight MH - Diabetes Mellitus, Type 2/*blood/psychology MH - Female MH - Follow-Up Studies MH - Glycated Hemoglobin/*metabolism MH - Humans MH - Life Style MH - Male MH - Middle Aged MH - Patient Compliance/psychology MH - Patient Education as Topic MH - *Quality of Life MH - Surveys and Questionnaires MH - Time EDAT- 2011/10/13 06:00 MHDA- 2012/05/04 06:00 CRDT- 2011/10/13 06:00 PHST- 2011/10/13 06:00 [entrez] PHST- 2011/10/13 06:00 [pubmed] PHST- 2012/05/04 06:00 [medline] AID - 10.1089/dia.2011.0116 [doi] PST - ppublish SO - Diabetes Technol Ther. 2012 Jan;14(1):59-64. doi: 10.1089/dia.2011.0116. Epub 2011 Oct 11.