PMID- 22001449
OWN - NLM
STAT- MEDLINE
DCOM- 20120213
LR  - 20190606
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 50
IP  - 20
DP  - 2011
TI  - Relationship between endoscopic findings and clinical severity in ischemic 
      colitis.
PG  - 2263-7
AB  - BACKGROUND AND AIM: The incidence of ischemic colitis (IC) in Japan has been 
      increasing due to the westernization of diet and the aging population. The aim of 
      this study was to evaluate the relationship between endoscopic findings and 
      clinical severity in IC. METHODS: This retrospective analysis included 106 cases 
      diagnosed with IC that were divided into two groups based on endoscopic findings 
      in the acute stage: redness and erosion (RE) versus longitudinal and 
      circumferential ulcers (LCU). The clinical variables were compared between the 
      two groups. In addition, we investigated the risk factors of IC associated with 
      the severity of the endoscopic findings by multivariate logistic regression 
      analysis. RESULTS: The percentage of cases presenting abdominal pain was 
      significantly higher in the LCU group than that in the RE group (p=0.002), as 
      were the baseline serum CRP levels (p=0.0001). The periods of hospitalization in 
      LCU group were longer than in the RE group (p=0.0001). Multivariate logistic 
      regression analysis indicated that ischemic heart disease (IHD) and connective 
      tissue disease were the independent explanatory factor associated with the 
      endoscopic severity of IC (p<0.05). CONCLUSION: We showed clearly that the two 
      endoscopic classifications were accurate indicators of severity and could be used 
      to anticipate severity of IC. Furthermore, we confirmed that IHD and connective 
      tissue disease were the exacerbating factor associated with the severity of 
      endoscopic findings in IC.
FAU - Beppu, Kazuko
AU  - Beppu K
AD  - Department of Gastroenterology, Juntendo University, School of Medicine, Japan. 
      kazukobp@juntendo.ac.jp
FAU - Osada, Taro
AU  - Osada T
FAU - Nagahara, Akihito
AU  - Nagahara A
FAU - Matsumoto, Kenshi
AU  - Matsumoto K
FAU - Shibuya, Tomoyoshi
AU  - Shibuya T
FAU - Sakamoto, Naoto
AU  - Sakamoto N
FAU - Otaka, Michiro
AU  - Otaka M
FAU - Terai, Takeshi
AU  - Terai T
FAU - Ogihara, Tatsuo
AU  - Ogihara T
FAU - Watanabe, Sumio
AU  - Watanabe S
LA  - eng
PT  - Journal Article
DEP - 20111015
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
MH  - Colitis, Ischemic/classification/*pathology
MH  - *Colonoscopy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Severity of Illness Index
EDAT- 2011/10/18 06:00
MHDA- 2012/02/14 06:00
CRDT- 2011/10/18 06:00
PHST- 2011/10/18 06:00 [entrez]
PHST- 2011/10/18 06:00 [pubmed]
PHST- 2012/02/14 06:00 [medline]
AID - JST.JSTAGE/internalmedicine/50.5349 [pii]
AID - 10.2169/internalmedicine.50.5349 [doi]
PST - ppublish
SO  - Intern Med. 2011;50(20):2263-7. doi: 10.2169/internalmedicine.50.5349. Epub 2011 
      Oct 15.