PMID- 22006586 OWN - NLM STAT- MEDLINE DCOM- 20120919 LR - 20150525 IS - 1522-2594 (Electronic) IS - 0740-3194 (Linking) VI - 67 IP - 6 DP - 2012 Jun TI - Spectroscopic imaging using concentrically circular echo-planar trajectories in vivo. PG - 1515-22 LID - 10.1002/mrm.23184 [doi] AB - An alternative to the standard echo-planar spectroscopic imaging technique is presented, spectroscopic imaging using concentrically circular echo-planar trajectories (SI-CONCEPT). In contrast to the conventional chemical shift imaging data, the sampled data from each set of concentric rings were regridded into Cartesian space. Usage of concentric k-space trajectories has the advantage of requiring significantly reduced slew rates than echo-planar spectroscopic imaging, allowing for the collection of higher spectral bandwidths and opening the door for high-bandwidth echo-planar styled spectroscopic imaging at higher magnetic fields. Before two-dimensional spatial and one-dimensional spectral encoding, the volume of interest was localized using the standard point-resolved spectroscopy sequence. The feasibility of using concentric k-space trajectories is demonstrated, and the spatial profiles and representative spectra are compared with the standard echo-planar spectroscopic imaging technique in a gray matter phantom containing metabolites at physiological concentrations and healthy human brain in vivo. The symmetric nature of the concentric circles also reduces the number of required excitations for a given resolution by a factor of two. Possible artifacts and limitations are discussed. CI - Copyright (c) 2011 Wiley Periodicals, Inc. FAU - Furuyama, Jon K AU - Furuyama JK AD - Department of Radiological Sciences, University of California, Los Angeles, California 90095, USA. FAU - Wilson, Neil E AU - Wilson NE FAU - Thomas, M Albert AU - Thomas MA LA - eng PT - Journal Article DEP - 20111017 PL - United States TA - Magn Reson Med JT - Magnetic resonance in medicine JID - 8505245 SB - IM MH - Adult MH - *Algorithms MH - Brain/*anatomy & histology/*metabolism MH - Echo-Planar Imaging/instrumentation/*methods MH - Humans MH - Image Enhancement/methods MH - Image Interpretation, Computer-Assisted/*methods MH - Magnetic Resonance Spectroscopy/*methods MH - Male MH - Phantoms, Imaging MH - Reproducibility of Results MH - Sensitivity and Specificity EDAT- 2011/10/19 06:00 MHDA- 2012/09/20 06:00 CRDT- 2011/10/19 06:00 PHST- 2011/04/18 00:00 [received] PHST- 2011/07/05 00:00 [revised] PHST- 2011/08/01 00:00 [accepted] PHST- 2011/10/19 06:00 [entrez] PHST- 2011/10/19 06:00 [pubmed] PHST- 2012/09/20 06:00 [medline] AID - 10.1002/mrm.23184 [doi] PST - ppublish SO - Magn Reson Med. 2012 Jun;67(6):1515-22. doi: 10.1002/mrm.23184. Epub 2011 Oct 17.