PMID- 22006600 OWN - NLM STAT- MEDLINE DCOM- 20120221 LR - 20111018 IS - 1897-4279 (Electronic) IS - 0022-9032 (Linking) VI - 69 IP - 10 DP - 2011 TI - Primary percutaneous coronary intervention during on- vs off-hours in patients with ST-elevation myocardial infarction. Results from EUROTRANSFER Registry. PG - 1017-22 AB - BACKGROUND: Primary percutaneous coronary intervention (PPCI) is regarded as the treatment of choice for ST elevation myocardial infarction (STEMI) patients. It has been emphasised that only experienced centres with round-the-clock cathlab facilities should perform PPCI. Some investigators have doubted whether PPCI performed during 'off-hours' is as effective and safe as that performed during regular hours. Papers supporting both possibilities have been published. AIM: To investigate whether off-hours PPCI is associated with impaired immediate and long-term outcomes based on a contemporary European registry study. METHODS: Consecutive data on STEMI patients referred for PPCI in hospital STEMI networks between November 2005 and January 2007 was gathered. Patients were divided into two groups: PPCI performed during 'on-hours' and PPCI performed during 'off-hours (including Saturdays and Sundays)'. RESULTS: Data from a total of 1,650 patients were collected in the EUROTRANSFER Registry. There were 1,005 patients in the off-hours group (61%) and 645 (39%) patients in the on-hours group. Patients in both groups did not differ in baseline demographics. Thrombolysis before admission to cathlab was more frequently administered to patients off-hours (4.1% vs 2.3%, p = 0.041). The PPCI complications were rare and occurred in similar frequency in the studied groups. Time from chest pain onset to diagnosis of STEMI was shorter in the off-hours group (173 +/- 210 vs 183 +/- 187, p = 0.007). In-hospital mortality was 3.4% in the on-hours group and 4.3% in the off-hours group (NS). CONCLUSIONS: The PPCI performed in high-volume, experienced invasive cardiology centres in Europe during off-hours is associated with a comparable outcome and safety profile as PPCI performed during regular working hours. FAU - Siudak, Zbigniew AU - Siudak Z AD - 2nd Department of Cardiology, University Hospital, Krakow, Poland. FAU - Rakowski, Tomasz AU - Rakowski T FAU - Dziewierz, Artur AU - Dziewierz A FAU - Skowronek, Jacek AU - Skowronek J FAU - Rutka, Joanna AU - Rutka J FAU - Bagienski, Maciej AU - Bagienski M FAU - Ranosz, Pawel AU - Ranosz P FAU - Dubiel, Jacek S AU - Dubiel JS FAU - Dudek, Dariusz AU - Dudek D LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Poland TA - Kardiol Pol JT - Kardiologia polska JID - 0376352 SB - IM CIN - Kardiol Pol. 2011;69(10):1023. PMID: 22006601 MH - After-Hours Care MH - Aged MH - Angioplasty, Balloon, Coronary/*adverse effects/mortality MH - Clinical Competence/*standards MH - Europe MH - Female MH - Hospital Mortality MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/mortality/*therapy MH - Registries MH - Risk Factors MH - Survival Analysis MH - Time Factors EDAT- 2011/10/19 06:00 MHDA- 2012/02/22 06:00 CRDT- 2011/10/19 06:00 PHST- 2011/10/19 06:00 [entrez] PHST- 2011/10/19 06:00 [pubmed] PHST- 2012/02/22 06:00 [medline] PST - ppublish SO - Kardiol Pol. 2011;69(10):1017-22.