PMID- 22016093
OWN - NLM
STAT- MEDLINE
DCOM- 20120412
LR  - 20120813
IS  - 1930-739X (Electronic)
IS  - 1930-7381 (Linking)
VI  - 20
IP  - 1
DP  - 2012 Jan
TI  - First Australian experiences with an oral volume restriction device to change 
      eating behaviors and assist with weight loss.
PG  - 126-33
LID - 10.1038/oby.2011.303 [doi]
AB  - Eating behaviors impact satiety and caloric intake so should be considered in any 
      weight-loss program. A novel custom-made oral device has been designed to be worn 
      in the upper palate while eating in order to slow eating-rate and aid weight 
      loss. The aim of this study was to assess the device's potential impact on 
      weight-loss and gain first impressions among overweight/obese Australians. Twenty 
      participants (M: 6, F: 14, mean age 36 years, BMI 27-33 kg/m(2)) were enrolled in 
      a 4-month open-label trial. Each received a device and nutritionist-delivered 
      diet plan. Weight, compliance, and acceptability were assessed fortnightly. 
      Anthropometry, biochemical and clinical outcomes were measured at baseline and 16 
      weeks. Sixteen participants completed the study. Mean weight-loss was 4.9 +/- 0.9 
      kg, or 5.2 +/- 0.9% initial bodyweight (P < 0.001, n = 20, intention-to-treat). 
      There were no significant adverse events (AEs), but 65% of participants required 
      device adjustment by the dentist. Compliance (defined as >5 uses/week) was 
      achieved by 80% of participants and correlated positively with weight-loss (R = 
      0.68, P = 0.001). All reported that the device was comfortable and reduced 
      bite-size, promoted chewing and slowed eating-rate. Most observed either no 
      change, or increased satiety, despite reduced meal sizes. For most, speech 
      difficulties discouraged device use in social settings. All reported greater 
      awareness of food choices, portion sizes and eating-rate. Subjective control of 
      dietary behaviors, measured by the Three Factor Eating Questionnaire (TFEQ), 
      improved significantly. The device should be explored as an adjunct to dietary 
      composition change in weight-management programs, to assist patients to modify 
      eating behaviors and achieve successful weight-loss.
FAU - McGee, Toni L
AU  - McGee TL
AD  - Human Neurotransmitters Laboratory and Vascular and Hypertension Division-Obesity 
      Research, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.
FAU - Grima, Mariee T
AU  - Grima MT
FAU - Hewson, Ian D
AU  - Hewson ID
FAU - Jones, Kay M
AU  - Jones KM
FAU - Duke, Ellen B
AU  - Duke EB
FAU - Dixon, John B
AU  - Dixon JB
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111020
PL  - United States
TA  - Obesity (Silver Spring)
JT  - Obesity (Silver Spring, Md.)
JID - 101264860
SB  - IM
MH  - Adult
MH  - Australia/epidemiology
MH  - Energy Intake
MH  - Equipment Design
MH  - Female
MH  - Humans
MH  - Male
MH  - Materials Testing
MH  - Obesity/epidemiology/prevention & control/*therapy
MH  - Patient Compliance
MH  - Prostheses and Implants
MH  - Treatment Outcome
MH  - *Weight Loss
EDAT- 2011/10/22 06:00
MHDA- 2012/04/13 06:00
CRDT- 2011/10/22 06:00
PHST- 2011/10/22 06:00 [entrez]
PHST- 2011/10/22 06:00 [pubmed]
PHST- 2012/04/13 06:00 [medline]
AID - oby2011303 [pii]
AID - 10.1038/oby.2011.303 [doi]
PST - ppublish
SO  - Obesity (Silver Spring). 2012 Jan;20(1):126-33. doi: 10.1038/oby.2011.303. Epub 
      2011 Oct 20.