PMID- 22018212
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20111123
LR  - 20211020
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 4
DP  - 2011 Oct 21
TI  - Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority 
      population: Mexican Americans from San Antonio, TX.
PG  - 433
LID - 10.1186/1756-0500-4-433 [doi]
AB  - BACKGROUND: Infection risks vary among individuals and between populations. Here 
      we present information on the seroprevalence of 13 common infectious agents in a 
      San Antonio-based sample of Mexican Americans. Mexican Americans represent the 
      largest and most rapidly growing minority population in the U.S., and they are 
      also considered a health disparities population. METHODS: We analyzed 1227 
      individuals for antibody titer to Chlamydophila pneumoniae, Helicobacter pylori, 
      Toxoplasma gondii, cytomegalovirus, Epstein-Barr virus, herpes simplex virus-1, 
      herpes simplex virus-2 (HSV-2), human herpesvirus-6 (HHV-6), varicella zoster 
      virus (VZV), adenovirus-36, hepatitis A virus, and influenza A and B. 
      Seroprevalence was examined as a function of sex, age, household income, and 
      education. RESULTS: Seroprevalence estimates ranged from 9% for T. gondii to 92% 
      for VZV, and were similar in both sexes except for HSV-2, which was more 
      prevalent in women. Many pathogens exhibited a significant seroprevalence change 
      over the examined age range (15-94 years), with 7 pathogens increasing and HHV-6 
      decreasing with age. Socioeconomic status significantly correlated with 
      serostatus for some pathogens. CONCLUSIONS: Our findings demonstrate substantial 
      seroprevalence rates of these common infections in this sample of Mexican 
      Americans from San Antonio, Texas that suffers from high rates of chronic 
      diseases including obesity and type-2 diabetes.
FAU - Rubicz, Rohina
AU  - Rubicz R
AD  - Department of Genetics, Texas Biomedical Research Institute, PO Box 760549, San 
      Antonio, TX 78245-0549, USA. rohina@txbiomedgenetics.org.
FAU - Leach, Charles T
AU  - Leach CT
FAU - Kraig, Ellen
AU  - Kraig E
FAU - Dhurandhar, Nikhil V
AU  - Dhurandhar NV
FAU - Grubbs, Barry
AU  - Grubbs B
FAU - Blangero, John
AU  - Blangero J
FAU - Yolken, Robert
AU  - Yolken R
FAU - Goring, Harald Hh
AU  - Goring HH
LA  - eng
GR  - P01 HL045522/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20111021
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
PMC - PMC3214184
EDAT- 2011/10/25 06:00
MHDA- 2011/10/25 06:01
PMCR- 2011/10/21
CRDT- 2011/10/25 06:00
PHST- 2011/06/20 00:00 [received]
PHST- 2011/10/21 00:00 [accepted]
PHST- 2011/10/25 06:00 [entrez]
PHST- 2011/10/25 06:00 [pubmed]
PHST- 2011/10/25 06:01 [medline]
PHST- 2011/10/21 00:00 [pmc-release]
AID - 1756-0500-4-433 [pii]
AID - 10.1186/1756-0500-4-433 [doi]
PST - epublish
SO  - BMC Res Notes. 2011 Oct 21;4:433. doi: 10.1186/1756-0500-4-433.