PMID- 22019223
OWN - NLM
STAT- MEDLINE
DCOM- 20120420
LR  - 20220310
IS  - 1879-1891 (Electronic)
IS  - 0002-9394 (Linking)
VI  - 153
IP  - 3
DP  - 2012 Mar
TI  - Evaluation of the nerve fiber layer and macula in the eyes of healthy children 
      using spectral-domain optical coherence tomography.
PG  - 552-559.e1
LID - 10.1016/j.ajo.2011.08.026 [doi]
AB  - PURPOSE: To determine the normative values of the peripapillary retinal nerve 
      fiber layer (RNFL), macular thickness, and macular volume in healthy children 
      using spectral-domain optical coherence tomography (SD-OCT) and analyze the 
      correlation of such values with age, refraction error, and biometric 
      measurements. DESIGN: Observational case series. METHODS: This institutional 
      study involved 107 eyes from 107 healthy pediatric patients (54 female, 53 male) 
      with ages between 6 and 16 years. After the biometric measurements and refractive 
      error values (in spherical equivalent) of the cases were obtained, the 
      peripapillary RNFL, macular thickness, and macular volume values were calculated 
      using the Spectralis OCT device. RESULTS: Among the study group, with an average 
      age of 10.46 +/- 2.94 years, the average axial length (AL) was 23.33 +/- 0.89 mm; the 
      average spherical equivalent (SE) value was -0.27 +/- 0.99 diopter. The average 
      peripapillary RNFL thickness was 106.45 +/- 9.41 mum; the average macular thickness 
      was 326.44 +/- 14.17 mum; and the average macular volume was 0.257 +/- 0.011 mm(3). 
      The aforementioned OCT measurements were not significantly correlated with age, 
      SE, or AL values (P > .05 for all). CONCLUSIONS: This study reports SD-OCT 
      findings among healthy pediatric cases. SD-OCT can be reliably used for pediatric 
      patients because of its short exposure time and high degree of image resolution.
CI  - Copyright A(c) 2012 Elsevier Inc. All rights reserved.
FAU - Turk, Adem
AU  - Turk A
AD  - Department of Ophthalmology, Karadeniz Technical University, School of Medicine, 
      Trabzon, Turkey. doktorademturk@yahoo.com
FAU - Ceylan, Osman Melih
AU  - Ceylan OM
FAU - Arici, Ceyhun
AU  - Arici C
FAU - Keskin, Soner
AU  - Keskin S
FAU - Erdurman, Cuneyt
AU  - Erdurman C
FAU - Durukan, Ali Hakan
AU  - Durukan AH
FAU - Mutlu, Fatih Mehmet
AU  - Mutlu FM
FAU - Altinsoy, Halil Ibrahim
AU  - Altinsoy HI
LA  - eng
PT  - Journal Article
DEP - 20111022
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
CIN - Am J Ophthalmol. 2012 Apr;153(4):774; author reply 774-5. PMID: 22445630
MH  - Adolescent
MH  - Aging/physiology
MH  - *Axons
MH  - Biometry
MH  - Child
MH  - Female
MH  - Humans
MH  - Macula Lutea/*anatomy & histology
MH  - Male
MH  - Optic Disk/*anatomy & histology
MH  - Reference Values
MH  - Refractive Errors/physiopathology
MH  - Reproducibility of Results
MH  - Retinal Ganglion Cells/*cytology
MH  - *Tomography, Optical Coherence
EDAT- 2011/10/25 06:00
MHDA- 2012/04/21 06:00
CRDT- 2011/10/25 06:00
PHST- 2011/06/18 00:00 [received]
PHST- 2011/08/12 00:00 [revised]
PHST- 2011/08/16 00:00 [accepted]
PHST- 2011/10/25 06:00 [entrez]
PHST- 2011/10/25 06:00 [pubmed]
PHST- 2012/04/21 06:00 [medline]
AID - S0002-9394(11)00668-4 [pii]
AID - 10.1016/j.ajo.2011.08.026 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2012 Mar;153(3):552-559.e1. doi: 10.1016/j.ajo.2011.08.026. Epub 
      2011 Oct 22.