PMID- 22032168
OWN - NLM
STAT- MEDLINE
DCOM- 20120802
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 6
DP  - 2011 Jun
TI  - [Determination of three sweeteners in vinegars by solid phase extraction-high 
      performance liquid chromatography/tandem mass spectrometry].
PG  - 554-7
AB  - A solid phase extraction-high performance liquid chromatography/electrospray 
      ionization-tandem mass spectrometry (SPE-HPLC/ESI-MS/MS) method for the 
      determination of 3 sweeteners (acesulfame (AK), sodium saccharin (SA), sodium 
      cyclamate (SC)) in vinegars has been developed. The sample was diluted with 
      acidic water, then purified and enriched with a weak anion exchange SPE column. 
      The HPLC separation was performed on a Pursuit C18 column (150 mm x 2.0 mm, 3 
      microm) by gradient elution with 10 mmol/L ammonium acetate containing 0.1% (v/v) 
      ammonia water and acetonitrile as the mobile phases. The analytes were detected 
      by ESI--MS/MS in multiple reaction monitoring (MRM) mode to satisfy qualitative 
      and quantitative detections. Good linearities (r2 > 0.99) were obtained over the 
      range of 0.01 - 0.50 mg/L. The limits of quantification (LOQs) for SA, AK and SC 
      were 10, 5 and 5 microg/kg, respectively. The average recoveries ranged from 
      72.1% to 96.8% at the spiked levels of 0.01 and 0.1 mg/L with the relative 
      standard deviations (RSDs) less than 15%. This method is accurate, highly 
      sensitive for qualitative and quantitative analysis of the 3 sweeteners in 
      vinegars.
FAU - Yin, Feng
AU  - Yin F
AD  - State Non-Staple Food Quality Supervision and Test Center, Beijing 100070, China. 
      fifayinfeng@yahoo.com.cn
FAU - Ding, Zhaowei
AU  - Ding Z
FAU - Cao, Xue
AU  - Cao X
FAU - Gao, Jie
AU  - Gao J
FAU - Jiang, Deming
AU  - Jiang D
FAU - Kuang, Denghui
AU  - Kuang D
FAU - Gu, Yanping
AU  - Gu Y
FAU - He, Guoliang
AU  - He G
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Cyclamates)
RN  - 0 (Sweetening Agents)
RN  - FST467XS7D (Saccharin)
RN  - Q40Q9N063P (Acetic Acid)
SB  - IM
MH  - Acetic Acid/*chemistry
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Cyclamates/analysis
MH  - Saccharin/analysis
MH  - Solid Phase Extraction/*methods
MH  - Spectrometry, Mass, Electrospray Ionization/methods
MH  - Sweetening Agents/*analysis
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2011/10/29 06:00
MHDA- 2012/08/03 06:00
CRDT- 2011/10/29 06:00
PHST- 2011/10/29 06:00 [entrez]
PHST- 2011/10/29 06:00 [pubmed]
PHST- 2012/08/03 06:00 [medline]
AID - 10.3724/sp.j.1123.2011.00554 [doi]
PST - ppublish
SO  - Se Pu. 2011 Jun;29(6):554-7. doi: 10.3724/sp.j.1123.2011.00554.