PMID- 22043215
OWN - NLM
STAT- MEDLINE
DCOM- 20120209
LR  - 20211020
IS  - 1654-9880 (Electronic)
IS  - 1654-9716 (Print)
IS  - 1654-9880 (Linking)
VI  - 4
DP  - 2011
TI  - Indications of decreasing human PTS concentrations in North West Russia.
LID - 10.3402/gha.v4i0.8427 [doi]
AB  - BACKGROUND: The Russian Arctic covers an enormous landmass with diverse 
      environments. It inhabits more than 20 different ethnic groups, all of them with 
      various living conditions and food traditions. Indigenous populations with a 
      traditional way of living are exposed to a large number of anthropogenic 
      pollutants, such as persistent organic pollutants (POPs) and toxic metals, mainly 
      through the diet. Human monitoring of persistent organic pollutants (POPs) and 
      heavy metals in the Russian Arctic has only been performed on irregular intervals 
      over the past 15 years, thus, there is still a lack of baseline data from many 
      ethnic groups and geographical regions. The aim of the current study was to 
      investigate concentrations of POPs and toxic metals in three groups of indigenous 
      people from the Russian Arctic. Plasma concentrations of POPs were measured in 
      one of the locations (Nelmin-Nos) in 2001-2003 which gave the unique opportunity 
      to compare concentrations over time in a small Russian arctic community. METHODS: 
      During 2009 and early 2010, 209 blood samples were collected from three different 
      study sites in North West Russia; Nelmin-Nos, Izhma and Usinsk. The three study 
      sites are geographically separated and the inhabitants are expected to have 
      different dietary habits and living conditions. All blood samples were analyzed 
      for POPs and toxic metals. RESULTS: PCB 153 was present in highest concentrations 
      of the 18 PCBs analyzed. p,p'-DDE and HCB were the two most dominating OC 
      pesticides. Males had higher concentrations of PCB 138, 153 and 180 than women 
      and age was a significant predictor of PCB 153, 180, HCB and p,p'-DDD. Males from 
      Izhma had significantly higher concentrations of HCB than males from the other 
      study sites and women from Usinsk had higher concentrations of p,p'-DDE. Parity 
      was a significant predictor of p,p'-DDE. Hg and Pb concentrations increased with 
      increasing age and males had significantly higher concentrations of Pb than 
      women. The study group from Izhma had significantly higher concentrations of Cd 
      when controlling for age and gender and the study group from Usinsk had higher 
      concentrations of Se than the others. Compared to the results from Nelmin-Nos in 
      2001-2003, a clear decrease in p,p'-DDE concentrations for both women and men was 
      observed. CONCLUSIONS: The current study indicates a significant reduction of 
      several PTSs in human blood samples from North West Russia over the past 10 
      years.
FAU - Rylander, Charlotta
AU  - Rylander C
AD  - Institute of Community Medicine, University of Tromso, Norway.
FAU - Sandanger, Torkjel M
AU  - Sandanger TM
FAU - Petrenya, Natalya
AU  - Petrenya N
FAU - Konoplev, Alexei
AU  - Konoplev A
FAU - Bojko, Evgeny
AU  - Bojko E
FAU - Odland, Jon Oyvind
AU  - Odland JO
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111025
PL  - United States
TA  - Glob Health Action
JT  - Global health action
JID - 101496665
RN  - 0 (Environmental Pollutants)
RN  - 0 (Metals)
RN  - 0 (Organic Chemicals)
RN  - 0 (Pesticides)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Arctic Regions
MH  - Child
MH  - *Diet
MH  - Environmental Exposure
MH  - Environmental Pollutants/*blood/toxicity
MH  - Female
MH  - Food Contamination
MH  - Humans
MH  - Male
MH  - Metals/*blood/toxicity
MH  - Middle Aged
MH  - Organic Chemicals/*blood/toxicity
MH  - Pesticides/*blood/toxicity
MH  - Population Groups/*statistics & numerical data
MH  - Russia
MH  - Sex Factors
MH  - Young Adult
PMC - PMC3203838
OTO - NOTNLM
OT  - North West Russia
OT  - PTS
OT  - decreasing levels
OT  - human blood
EDAT- 2011/11/02 06:00
MHDA- 2012/02/10 06:00
PMCR- 2011/10/25
CRDT- 2011/11/02 06:00
PHST- 2011/08/01 00:00 [received]
PHST- 2011/09/21 00:00 [revised]
PHST- 2011/09/22 00:00 [accepted]
PHST- 2011/11/02 06:00 [entrez]
PHST- 2011/11/02 06:00 [pubmed]
PHST- 2012/02/10 06:00 [medline]
PHST- 2011/10/25 00:00 [pmc-release]
AID - GHA-4-8427 [pii]
AID - 10.3402/gha.v4i0.8427 [doi]
PST - ppublish
SO  - Glob Health Action. 2011;4. doi: 10.3402/gha.v4i0.8427. Epub 2011 Oct 25.