PMID- 22048577
OWN - NLM
STAT- MEDLINE
DCOM- 20120405
LR  - 20181201
IS  - 1998-3603 (Electronic)
IS  - 0970-9290 (Linking)
VI  - 22
IP  - 3
DP  - 2011 May-Jun
TI  - Assessment of combination techniques in enhancing the regenerative potential of 
      tricalcium phosphate graft in treatment of infrabony periodontal defects.
PG  - 391-5
LID - 10.4103/0970-9290.87059 [doi]
AB  - AIMS: The purpose of the present study was to evaluate and compare the clinical 
      outcome of infrabony defects following reconstructive surgery with the use of 
      tricalcium phosphate (TCP) alone; TCP and citric acid (CA) root conditioning; and 
      TCP, CA, and oxidized regenerated cellulose (ORC) membrane. MATERIALS AND 
      METHODS: Thirty-nine systemically healthy subjects with vertical infrabony defect 
      were initially selected based on intraoral periapical radiographs and clinical 
      examination to record probing pocket depth (PPD) and clinical attachment level 
      (CAL). Only 21 defects revealed two-walled configuration on surgical debridement. 
      These defects were selected and randomly allotted to the study groups. Group 1 
      defects were treated with TCP, group 2 with TCP+CA, and group 3 with TCP+CA+ORC. 
      PPD, CAL, defect depth (DD), and level of alveolar crest (AC) were evaluated at 
      the time of initial surgery and after 6 months at surgical re-entry. These 
      measurements were utilized to calculate PPD reduction, CAL gain, defect fill 
      (DF), %defect fill (%DF), and crestal resorption (CR). STATISTICAL ANALYSIS: A 
      paired t-test was used for assessing changes in each group. Unpaired t-test was 
      used for intergroup comparisons. RESULTS: All three groups showed statistically 
      significant PPD reduction, CAL gain, DF, and %DF, but insignificant CR at the end 
      of 6 months. On intergroup comparison, no statistically significant differences 
      were noted between the groups for all the parameters. CONCLUSION: Efficacy of 
      combination techniques using TCP+CA; TCP+CA+ORC in treatment of periodontal 
      infrabony defects is at least equal to that of TCP alone.
FAU - Saini, Ashish
AU  - Saini A
AD  - Department of Periodontics, Chandra Dental College and Hospital, Safedabad, 
      Barabanki, India. ashishsaini2005@yahoo.co.in
FAU - Singh, Meghna
AU  - Singh M
FAU - Lal, Nand
AU  - Lal N
FAU - Dixit, Jaya
AU  - Dixit J
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - India
TA  - Indian J Dent Res
JT  - Indian journal of dental research : official publication of Indian Society for 
      Dental Research
JID - 9202990
RN  - 0 (Biocompatible Materials)
RN  - 0 (Bone Substitutes)
RN  - 0 (Calcium Phosphates)
RN  - 0 (Cellulose, Oxidized)
RN  - 0 (Membranes, Artificial)
RN  - 2968PHW8QP (Citric Acid)
RN  - K4C08XP666 (tricalcium phosphate)
MH  - Adult
MH  - Alveolar Bone Loss/*therapy
MH  - Biocompatible Materials/*therapeutic use
MH  - Bone Regeneration/drug effects
MH  - Bone Substitutes/therapeutic use
MH  - Calcium Phosphates/*therapeutic use
MH  - Cellulose, Oxidized/*therapeutic use
MH  - Citric Acid/therapeutic use
MH  - Combined Modality Therapy
MH  - Follow-Up Studies
MH  - Guided Tissue Regeneration, Periodontal/*methods
MH  - Humans
MH  - Membranes, Artificial
MH  - Middle Aged
MH  - Osseointegration/drug effects
MH  - Periodontal Index
MH  - Tissue Conditioning, Dental/*methods
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2011/11/04 06:00
MHDA- 2012/04/06 06:00
CRDT- 2011/11/04 06:00
PHST- 2011/11/04 06:00 [entrez]
PHST- 2011/11/04 06:00 [pubmed]
PHST- 2012/04/06 06:00 [medline]
AID - IndianJDentRes_2011_22_3_391_87059 [pii]
AID - 10.4103/0970-9290.87059 [doi]
PST - ppublish
SO  - Indian J Dent Res. 2011 May-Jun;22(3):391-5. doi: 10.4103/0970-9290.87059.