PMID- 2205293
OWN - NLM
STAT- MEDLINE
DCOM- 19901023
LR  - 20190719
IS  - 0007-1145 (Print)
IS  - 0007-1145 (Linking)
VI  - 64
IP  - 1
DP  - 1990 Jul
TI  - Influence of malaria infection on peroxyl-radical trapping capacity in plasma 
      from rural and urban Thai adults.
PG  - 257-71
AB  - Measurement of peroxyl-radical trapping capacity (TRAP) were made in plasma from 
      patients with malaria from a rural and an urban Thai community. The results were 
      compared with those from control subjects living in the same areas and chosen to 
      match the patients closely. Measurements were also made of various antioxidants 
      including nutritional indices vitamin C and alpha-tocopherol and the 
      non-nutritional indices urate and protein-sulphydryl. Parasite counts, 
      temperature on examination and the duration of illness were recorded together 
      with measurements of plasma caeruloplasmin (EC 1.16.3.1), retinol and 
      malondialdehyde (MDA). In general, most measurements made in the villagers were 
      lower than those in the comparable urban groups. The exceptions were 
      caeruloplasmin and MDA when the latter was expressed as MDA:cholesterol ratio. 
      TRAP values were extremely low in 50% of the villagers and 25% of the urban 
      patients with malaria and these results correlated with retinol and vitamin C and 
      inversely with malonaldehyde. The results suggested that low TRAP values are 
      associated with lipid peroxidation and that vitamin C and possibly retinol may be 
      destroyed by the oxidative conditions present in the plasma in this disease.
FAU - Thurnham, D I
AU  - Thurnham DI
AD  - Clinical Investigation Unit, Dudley Road Hospital, Birmingham.
FAU - Singkamani, R
AU  - Singkamani R
FAU - Kaewichit, R
AU  - Kaewichit R
FAU - Wongworapat, K
AU  - Wongworapat K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Free Radicals)
RN  - 11103-57-4 (Vitamin A)
RN  - 1406-18-4 (Vitamin E)
RN  - 4Y8F71G49Q (Malondialdehyde)
RN  - 97C5T2UQ7J (Cholesterol)
RN  - EC 1.16.3.1 (Ceruloplasmin)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Animals
MH  - Ceruloplasmin/metabolism
MH  - Child
MH  - Cholesterol/blood
MH  - Female
MH  - Free Radicals
MH  - Humans
MH  - Lipid Peroxidation/*physiology
MH  - Malaria/*blood
MH  - Male
MH  - Malondialdehyde/blood
MH  - Middle Aged
MH  - Plasmodium falciparum/isolation & purification
MH  - Rural Population
MH  - Thailand
MH  - Urban Population
MH  - Vitamin A/blood
MH  - Vitamin E/blood
EDAT- 1990/07/01 00:00
MHDA- 1990/07/01 00:01
CRDT- 1990/07/01 00:00
PHST- 1990/07/01 00:00 [pubmed]
PHST- 1990/07/01 00:01 [medline]
PHST- 1990/07/01 00:00 [entrez]
AID - S0007114590001027 [pii]
AID - 10.1079/bjn19900027 [doi]
PST - ppublish
SO  - Br J Nutr. 1990 Jul;64(1):257-71. doi: 10.1079/bjn19900027.