PMID- 22071704
OWN - NLM
STAT- MEDLINE
DCOM- 20120203
LR  - 20240109
IS  - 1938-3207 (Electronic)
IS  - 0002-9165 (Print)
IS  - 0002-9165 (Linking)
VI  - 94
IP  - 6
DP  - 2011 Dec
TI  - Mediterranean-style diet and risk of ischemic stroke, myocardial infarction, and 
      vascular death: the Northern Manhattan Study.
PG  - 1458-64
LID - 10.3945/ajcn.111.012799 [doi]
AB  - BACKGROUND: A dietary pattern common in regions near the Mediterranean appears to 
      reduce risk of all-cause mortality and ischemic heart disease. Data on blacks and 
      Hispanics in the United States are lacking, and to our knowledge only one study 
      has examined a Mediterranean-style diet (MeDi) in relation to stroke. OBJECTIVE: 
      In this study, we examined an MeDi in relation to vascular events. DESIGN: The 
      Northern Manhattan Study is a population-based cohort to determine stroke 
      incidence and risk factors (mean +/- SD age of participants: 69 +/- 10 y; 64% women; 
      55% Hispanic, 21% white, and 24% black). Diet was assessed at baseline by using a 
      food-frequency questionnaire in 2568 participants. A higher score on a 0-9 scale 
      represented increased adherence to an MeDi. The relation between the MeDi score 
      and risk of ischemic stroke, myocardial infarction (MI), and vascular death was 
      assessed with Cox models, with control for sociodemographic and vascular risk 
      factors. RESULTS: The MeDi-score distribution was as follows: 0-2 (14%), 3 (17%), 
      4 (22%), 5 (22%), and 6-9 (25%). Over a mean follow-up of 9 y, 518 vascular 
      events accrued (171 ischemic strokes, 133 MIs, and 314 vascular deaths). The MeDi 
      score was inversely associated with risk of the composite outcome of ischemic 
      stroke, MI, or vascular death (P-trend = 0.04) and with vascular death 
      specifically (P-trend = 0.02). Moderate and high MeDi scores were marginally 
      associated with decreased risk of MI. There was no association with ischemic 
      stroke. CONCLUSIONS: Higher consumption of an MeDi was associated with decreased 
      risk of vascular events. Results support the role of a diet rich in fruit, 
      vegetables, whole grains, fish, and olive oil in the promotion of ideal 
      cardiovascular health.
FAU - Gardener, Hannah
AU  - Gardener H
AD  - Evelyn F McKnight Brain Institute, Department of Neurology, Miller School of 
      Medicine, University of Miami, FL 33136, USA.
FAU - Wright, Clinton B
AU  - Wright CB
FAU - Gu, Yian
AU  - Gu Y
FAU - Demmer, Ryan T
AU  - Demmer RT
FAU - Boden-Albala, Bernadette
AU  - Boden-Albala B
FAU - Elkind, Mitchell S V
AU  - Elkind MS
FAU - Sacco, Ralph L
AU  - Sacco RL
FAU - Scarmeas, Nikolaos
AU  - Scarmeas N
LA  - eng
GR  - R37 NS 29993/NS/NINDS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20111109
PL  - United States
TA  - Am J Clin Nutr
JT  - The American journal of clinical nutrition
JID - 0376027
SB  - IM
CIN - Am J Clin Nutr. 2012 Jun;95(6):1495; author reply 1495-6. PMID: 22611077
MH  - Aged
MH  - Black People
MH  - Brain Ischemia/epidemiology/etiology/*prevention & control
MH  - Diet Surveys
MH  - *Diet, Mediterranean
MH  - Female
MH  - Hispanic or Latino
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/epidemiology/etiology/*prevention & control
MH  - New York City/epidemiology
MH  - Proportional Hazards Models
MH  - Prospective Studies
MH  - Risk Factors
MH  - Stroke/epidemiology/etiology/*prevention & control
MH  - Surveys and Questionnaires
MH  - Vascular Diseases/etiology/mortality/*prevention & control
MH  - White People
PMC - PMC3252546
EDAT- 2011/11/11 06:00
MHDA- 2012/02/04 06:00
PMCR- 2012/12/01
CRDT- 2011/11/11 06:00
PHST- 2011/11/11 06:00 [entrez]
PHST- 2011/11/11 06:00 [pubmed]
PHST- 2012/02/04 06:00 [medline]
PHST- 2012/12/01 00:00 [pmc-release]
AID - S0002-9165(23)02513-3 [pii]
AID - 012799 [pii]
AID - 10.3945/ajcn.111.012799 [doi]
PST - ppublish
SO  - Am J Clin Nutr. 2011 Dec;94(6):1458-64. doi: 10.3945/ajcn.111.012799. Epub 2011 
      Nov 9.