PMID- 22076268
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20111123
LR  - 20211021
IS  - 2156-7085 (Electronic)
IS  - 2156-7085 (Linking)
VI  - 2
IP  - 11
DP  - 2011 Nov 1
TI  - Thermal intravascular photoacoustic imaging.
PG  - 3072-8
LID - 10.1364/BOE.2.003072 [doi]
AB  - Intravascular photoacoustics (IVPA)-a minimally invasive imaging technique with 
      contrast related to optical absorption properties of tissue, can be used to 
      visualize atherosclerotic plaques. However, the amplitude of photoacoustic 
      signals is also related to a temperature dependent, tissue specific parameter-the 
      Gruneisen parameter. Therefore, photoacoustic signals measured at different 
      temperatures may reveal information about tissue composition. In this study, 
      thermal IVPA (tIVPA) imaging was introduced. The imaging studies were performed 
      using an ex vivo atherosclerotic rabbit aorta. Temperature dependent 
      photoacoustic responses from lipid in plaques and lipid in periadventitial tissue 
      were different, thus allowing tIVPA images to delineate the location of 
      lipid-rich plaques. The results indicate that tIVPA imaging has a potential to 
      characterize tissue composition in atherosclerotic vessels.
FAU - Wang, Bo
AU  - Wang B
AD  - Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 
      78712, USA.
FAU - Emelianov, Stanislav
AU  - Emelianov S
LA  - eng
GR  - R01 HL096981/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20111013
PL  - United States
TA  - Biomed Opt Express
JT  - Biomedical optics express
JID - 101540630
PMC - PMC3207376
OTO - NOTNLM
OT  - (110.5120) Photoacoustic imaging
OT  - (110.7170) Ultrasound
OT  - (170.0170) Medical optics and biotechnology
OT  - (170.6935) Tissue characterization
EDAT- 2011/11/15 06:00
MHDA- 2011/11/15 06:01
PMCR- 2011/10/13
CRDT- 2011/11/15 06:00
PHST- 2011/08/02 00:00 [received]
PHST- 2011/09/30 00:00 [revised]
PHST- 2011/10/03 00:00 [accepted]
PHST- 2011/11/15 06:00 [entrez]
PHST- 2011/11/15 06:00 [pubmed]
PHST- 2011/11/15 06:01 [medline]
PHST- 2011/10/13 00:00 [pmc-release]
AID - 152125 [pii]
AID - 10.1364/BOE.2.003072 [doi]
PST - ppublish
SO  - Biomed Opt Express. 2011 Nov 1;2(11):3072-8. doi: 10.1364/BOE.2.003072. Epub 2011 
      Oct 13.