PMID- 22088550
OWN - NLM
STAT- MEDLINE
DCOM- 20120504
LR  - 20111117
IS  - 2542-5641 (Electronic)
IS  - 0366-6999 (Linking)
VI  - 124
IP  - 20
DP  - 2011 Oct
TI  - Coexisting ankylosing spondylitis and rheumatoid arthritis: a case report with 
      literature review.
PG  - 3430-2
AB  - A 30-year-old female patient with coexisting ankylosing spondylitis and 
      rheumatoid arthritis was diagnosed and treated. The human leukocyte antigen 
      (HLA)-B27 is a predisposing factor of ankylosing spondylitis and HLA-DR4 is a 
      predisposing factor of rheumatoid arthritis. This patient was HLA-B27 and HLA-DR4 
      positive, and ankylosing spondylitis manifested before rheumatoid arthritis. 
      After disease modifying anti-rheumatic drugs successfully arrested ankylosing 
      spondylitis activity the patient conceived and delivered a healthy baby. One year 
      later, she developed peripheral polyarthritis and was diagnosed with rheumatoid 
      arthritis. We hypothesized that pregnancy may be one of the environmental factors 
      that can activate rheumatoid arthritis, and that disease modifying anti-rheumatic 
      drugs play an important role in keeping the disease under control.
FAU - Guo, Ying-Ying
AU  - Guo YY
AD  - Department of Rheumatology and Immunology, Shengjing Hospital of China Medical 
      University, Shenyang, Liaoning 110004, China.
FAU - Yang, Li-Li
AU  - Yang LL
FAU - Cui, Hua-Dong
AU  - Cui HD
FAU - Zhao, Shuai
AU  - Zhao S
FAU - Zhang, Ning
AU  - Zhang N
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - China
TA  - Chin Med J (Engl)
JT  - Chinese medical journal
JID - 7513795
RN  - 0 (HLA-B27 Antigen)
RN  - 0 (HLA-DR4 Antigen)
SB  - IM
MH  - Adult
MH  - Arthritis, Rheumatoid/*diagnosis/metabolism
MH  - Female
MH  - HLA-B27 Antigen/metabolism
MH  - HLA-DR4 Antigen/metabolism
MH  - Humans
MH  - Spondylitis, Ankylosing/*diagnosis/metabolism
EDAT- 2011/11/18 06:00
MHDA- 2012/05/05 06:00
CRDT- 2011/11/18 06:00
PHST- 2011/11/18 06:00 [entrez]
PHST- 2011/11/18 06:00 [pubmed]
PHST- 2012/05/05 06:00 [medline]
PST - ppublish
SO  - Chin Med J (Engl). 2011 Oct;124(20):3430-2.