PMID- 22094328
OWN - NLM
STAT- MEDLINE
DCOM- 20120918
LR  - 20120514
IS  - 1877-783X (Electronic)
IS  - 1877-7821 (Linking)
VI  - 36
IP  - 3
DP  - 2012 Jun
TI  - Near infrared spectroscopy combined with least squares support vector machines 
      and fuzzy rule-building expert system applied to diagnosis of endometrial 
      carcinoma.
PG  - 317-23
LID - 10.1016/j.canep.2011.10.009 [doi]
AB  - OBJECTIVE: The feasibility of early diagnosis of endometrial carcinoma was 
      studied by least squares support vector machines (LS-SVM) and fuzzy rule-building 
      expert system (FuRES) that classified near infrared (NIR) spectra of tissues. 
      METHODS: NIR spectra of 77 specimens of endometrium were collected. The spectra 
      were pretreated by principal component orthogonal signal correction (PC-OSC) and 
      direct orthogonal signal correction (DOSC) methods to improve the signal-to-noise 
      ratio (SNR) and remove the influences of background and baseline. The effects of 
      modeling parameters were investigated using bootstrapped Latin-partition methods. 
      RESULTS: The optimal LS-SVM model of the PC-OSC pretreatment method successfully 
      classified the samples with prediction accuracies of 96.8+/-1.4%. CONCLUSIONS: The 
      proposed procedure proved to be rapid and convenient, which is suitable to be 
      developed as a non-invasive diagnosis method for cancer tissue.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Yang, Fan
AU  - Yang F
AD  - Department of Chemistry, Capital Normal University, Beijing, China.
FAU - Tian, Jing
AU  - Tian J
FAU - Xiang, Yuhong
AU  - Xiang Y
FAU - Zhang, Zhuoyong
AU  - Zhang Z
FAU - Harrington, Peter de B
AU  - Harrington Pde B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111117
PL  - Netherlands
TA  - Cancer Epidemiol
JT  - Cancer epidemiology
JID - 101508793
SB  - IM
MH  - Adult
MH  - Aged
MH  - Endometrial Neoplasms/*diagnosis/pathology
MH  - Female
MH  - Fuzzy Logic
MH  - Humans
MH  - Least-Squares Analysis
MH  - Middle Aged
MH  - *Models, Theoretical
MH  - Signal-To-Noise Ratio
MH  - Spectroscopy, Near-Infrared/*methods
MH  - Young Adult
EDAT- 2011/11/19 06:00
MHDA- 2012/09/19 06:00
CRDT- 2011/11/19 06:00
PHST- 2011/07/29 00:00 [received]
PHST- 2011/10/18 00:00 [revised]
PHST- 2011/10/20 00:00 [accepted]
PHST- 2011/11/19 06:00 [entrez]
PHST- 2011/11/19 06:00 [pubmed]
PHST- 2012/09/19 06:00 [medline]
AID - S1877-7821(11)00161-5 [pii]
AID - 10.1016/j.canep.2011.10.009 [doi]
PST - ppublish
SO  - Cancer Epidemiol. 2012 Jun;36(3):317-23. doi: 10.1016/j.canep.2011.10.009. Epub 
      2011 Nov 17.