PMID- 22097788
OWN - NLM
STAT- MEDLINE
DCOM- 20120906
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 7
DP  - 2011 Jul
TI  - [Stir rod sorptive extraction with poly(methacrylic acid-co-ethylene 
      dimethacrylate) as coating and its application to the analysis of sulfonamides in 
      milk samples].
PG  - 624-30
AB  - A poly(methacrylic acid-co-ethylene dimethacrylate) polymer(poly(MAA-co-EDMA)) 
      was prepared via in-situ polymerization on the outside surface of vial glass 
      insert and used as stir rod sorptive extraction (SRSE) coating. The extraction 
      performance of the polymer coating toward four sulfonamides (SAs) was 
      investigated. The effects of several parameters to SRSE, such as the pH value, 
      inorganic salt and organic phase concentrations of the sample matrix, were 
      investigated. It demonstrated that the sulfonamides were captured on the 
      poly(MAA-co-EDMA) coating mainly through cation-exchange and hydrophobic 
      interactions. A novel approach is presented for the determination of four 
      sulfonamide antibacterial residues in milk samples by coupling SRSE to liquid 
      chromatography and electrospray ionization mass spectrometry (SRSE/LC-ESI-MS). In 
      this method, the detection limits (S/N = 3) of 0.11-0.52 microg/L and 
      quantification limits (S/N = 10) of 0.35-1.72 microg/L were obtained. The method 
      showed good linearity in the range of 1-500 microg/L. Good method reproducibility 
      was also found by intra- and inter-day precisions, yielding the relative standard 
      deviations (RSDs) less than 11.3%. The results demonstrated that the proposed 
      method is simple, sensitive, low cost and suitable for the determination of 
      sulfonamides in milk samples.
FAU - Ma, Qiao
AU  - Ma Q
AD  - Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of 
      Education), Department of Chemistry, Wuhan University, Wuhan 430072, China.
FAU - Yu, Qiongwei
AU  - Yu Q
FAU - Luo, Yanbo
AU  - Luo Y
FAU - Feng, Yuqi
AU  - Feng Y
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Acrylic Resins)
RN  - 0 (Eudragit L100-55)
RN  - 0 (Sulfonamides)
SB  - IM
MH  - Acrylic Resins/chemistry
MH  - Animals
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Drug Residues/*analysis
MH  - Food Analysis/methods
MH  - Milk/*chemistry
MH  - Spectrometry, Mass, Electrospray Ionization/*methods
MH  - Sulfonamides/*analysis
EDAT- 2011/11/22 06:00
MHDA- 2012/09/07 06:00
CRDT- 2011/11/22 06:00
PHST- 2011/11/22 06:00 [entrez]
PHST- 2011/11/22 06:00 [pubmed]
PHST- 2012/09/07 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2011 Jul;29(7):624-30.