PMID- 22097790
OWN - NLM
STAT- MEDLINE
DCOM- 20120906
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 7
DP  - 2011 Jul
TI  - [Determination of spinosyns A and D residues in food by high performance liquid 
      chromatography-tandem mass spectrometry].
PG  - 637-42
AB  - A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/ MS) 
      method was established for the determination of spinosyns A and D residues in 
      foodstuffs. The food samples were extracted with acetonitrile-water (50:50, v/v), 
      and then purified by an HLB solid phase extraction (SPE) column. The analytes 
      were determined by HPLC-MS/MS and quantified by external standard method. The 
      mass spectrometric detection was operated with electrospray in positive 
      ionization mode and the spinosyns A and D were identified in multiple reaction 
      monitoring (MRM) mode. The linear range of the method was 1-20 microg/L, with the 
      correlation coefficient (r2) of 0.999 9. No significant matrix effect was found 
      for spiked samples. The recoveries of spinosyns A and D spiked in food were 
      76.2%-114.0% at the spiked levels of 1-10 microg/kg. The relative standard 
      deviations (RSDs) were less than 10%. The limits of detection (LODs) and 
      quantification (LOQs) were 0.2 microg/kg and 0.5 microg/kg for spinosyn A, 0.5 
      microg/kg and 1.0 microg/kg for spinosyn D, respectively. The proposed procedure 
      was applied to the analysis of 969 real samples from Xiamen, Fujian Province 
      (China), of which 15 positive samples were found. The results showed that the 
      proposed method is sensitive and accurate for the determination of spinosyns A 
      and D in foodstuffs.
FAU - Zhang, Jin
AU  - Zhang J
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Yang, Lizhong
AU  - Yang L
FAU - Lin, Liyi
AU  - Lin L
FAU - Chen, Luping
AU  - Chen L
FAU - Zhou, Yu
AU  - Zhou Y
FAU - Xu, Dunming
AU  - Xu D
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Macrolides)
RN  - 0 (Pesticide Residues)
RN  - 0 (spinosyn A)
RN  - 0 (spinosyn D)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Analysis/methods
MH  - Food Contamination/*analysis
MH  - Macrolides/*analysis
MH  - Pesticide Residues/analysis
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2011/11/22 06:00
MHDA- 2012/09/07 06:00
CRDT- 2011/11/22 06:00
PHST- 2011/11/22 06:00 [entrez]
PHST- 2011/11/22 06:00 [pubmed]
PHST- 2012/09/07 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2011 Jul;29(7):637-42.