PMID- 22099788
OWN - NLM
STAT- MEDLINE
DCOM- 20140930
LR  - 20111121
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 43
IP  - 9
DP  - 2011 Nov
TI  - Minor histocompatibility antigens as risk factor for poor prognosis in kidney 
      transplantation.
PG  - 3319-23
LID - 10.1016/j.transproceed.2011.09.007 [doi]
AB  - Progress in transplantation has relied on similar human leukocyte antigen (HLA) 
      matching between the donor and the patient, while the role of other immunologic 
      factors like non-HLA markers including minor histocompatibility antigens (miHA) 
      are currently in the forefront. miHA are polymorphic proteins that vary even in 
      monozygotic twins. The best known is the H-Y antigen, but there are also other 
      autosomal miHA and MICA (MHC class I chain-related gene A). miHA have been well 
      studied in transplantation of hematopoietic precursors, but not in solid organ 
      transplantation. The most important studies in this field relate to 
      incompatibility of H-Y antigen as a risk factor in kidney transplantation, 
      although the findings are still inconclusive. This review presents the role of 
      minor histocompatibility antigens in solid organ transplantation, especially of 
      the kidney.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Pabon, M A
AU  - Pabon MA
AD  - Organ and Tissues Transplant Group, Medical School, National University of 
      Colombia, Bogota, Colombia. mapabonp@unal.edu.co
FAU - Navarro, C E
AU  - Navarro CE
FAU - Martin, R
AU  - Martin R
FAU - Rodriguez, M
AU  - Rodriguez M
FAU - Martin, I
AU  - Martin I
FAU - Gaitan, L
AU  - Gaitan L
FAU - Gomez, A
AU  - Gomez A
FAU - Lozano, E
AU  - Lozano E
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (H-Y Antigen)
RN  - 0 (Histocompatibility Antigens Class I)
RN  - 0 (MHC class I-related chain A)
RN  - 0 (Minor Histocompatibility Antigens)
SB  - IM
MH  - Animals
MH  - Graft Rejection
MH  - Graft Survival
MH  - Graft vs Host Disease/immunology
MH  - H-Y Antigen/immunology
MH  - Histocompatibility/immunology
MH  - Histocompatibility Antigens Class I/metabolism
MH  - Histocompatibility Testing
MH  - Humans
MH  - Kidney Transplantation/*methods
MH  - Mice
MH  - Minor Histocompatibility Antigens/*immunology/metabolism
MH  - Prognosis
MH  - Renal Insufficiency, Chronic/therapy
MH  - Risk Factors
MH  - Treatment Outcome
EDAT- 2011/11/22 06:00
MHDA- 2014/10/01 06:00
CRDT- 2011/11/22 06:00
PHST- 2011/11/22 06:00 [entrez]
PHST- 2011/11/22 06:00 [pubmed]
PHST- 2014/10/01 06:00 [medline]
AID - S0041-1345(11)01182-1 [pii]
AID - 10.1016/j.transproceed.2011.09.007 [doi]
PST - ppublish
SO  - Transplant Proc. 2011 Nov;43(9):3319-23. doi: 10.1016/j.transproceed.2011.09.007.