PMID- 22106073 OWN - NLM STAT- MEDLINE DCOM- 20120124 LR - 20220419 IS - 1098-4275 (Electronic) IS - 0031-4005 (Linking) VI - 128 IP - 6 DP - 2011 Dec TI - The safety of pediatric acupuncture: a systematic review. PG - e1575-87 LID - 10.1542/peds.2011-1091 [doi] AB - CONTEXT: Acupuncture is increasingly used in children; however, the safety of pediatric acupuncture has yet to be reported from systematic review. OBJECTIVE: To identify adverse events (AEs) associated with needle acupuncture in children. METHODS: Eighteen databases were searched, from inception to September 2010, irrespective of language. Inclusion criteria were that the study (1) was original peer-reviewed research, (2) included children from birth to 17 years, inclusively, (3) involved needle acupuncture, and (4) included assessment of AEs in a child. Safety data were extracted from all included studies. RESULTS: Of 9537 references identified, 450 were assessed for inclusion. Twenty-eight reports were included, and searches of reference lists identified 9 additional reports (total: 37). A total of 279 AEs were identified, 146 from randomized controlled trials, 95 from cohort studies, and 38 from case reports/series. Of the AEs, 25 were serious (12 cases of thumb deformity, 5 infections, and 1 case each of cardiac rupture, pneumothorax, nerve impairment, subarachnoid hemorrhage, intestinal obstruction, hemoptysis, reversible coma, and overnight hospitalization), 1 was moderate (infection), and 253 were mild. The mild AEs included pain, bruising, bleeding, and worsening of symptoms. We calculated a mild AE incidence per patient of 168 in 1422 patients (11.8% [95% confidence interval: 10.1-13.5]). CONCLUSIONS: Of the AEs associated with pediatric needle acupuncture, a majority of them were mild in severity. Many of the serious AEs might have been caused by substandard practice. Our results support those from adult studies, which have found that acupuncture is safe when performed by appropriately trained practitioners. FAU - Adams, Denise AU - Adams D AD - Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada. FAU - Cheng, Florence AU - Cheng F FAU - Jou, Hsing AU - Jou H FAU - Aung, Steven AU - Aung S FAU - Yasui, Yutaka AU - Yasui Y FAU - Vohra, Sunita AU - Vohra S LA - eng GR - Canadian Institutes of Health Research/Canada PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PT - Systematic Review DEP - 20111121 PL - United States TA - Pediatrics JT - Pediatrics JID - 0376422 SB - IM MH - Acupuncture Therapy/*adverse effects MH - Adolescent MH - Child MH - Child, Preschool MH - Humans MH - Infant MH - Infant, Newborn MH - Severity of Illness Index EDAT- 2011/11/23 06:00 MHDA- 2012/01/25 06:00 CRDT- 2011/11/23 06:00 PHST- 2011/11/23 06:00 [entrez] PHST- 2011/11/23 06:00 [pubmed] PHST- 2012/01/25 06:00 [medline] AID - peds.2011-1091 [pii] AID - 10.1542/peds.2011-1091 [doi] PST - ppublish SO - Pediatrics. 2011 Dec;128(6):e1575-87. doi: 10.1542/peds.2011-1091. Epub 2011 Nov 21.