PMID- 22112544
OWN - NLM
STAT- MEDLINE
DCOM- 20121029
LR  - 20211021
IS  - 1877-783X (Electronic)
IS  - 1877-7821 (Print)
IS  - 1877-7821 (Linking)
VI  - 36
IP  - 4
DP  - 2012 Aug
TI  - Factors associated with inadequate colorectal cancer screening with flexible 
      sigmoidoscopy.
PG  - 395-9
LID - 10.1016/j.canep.2011.10.013 [doi]
AB  - BACKGROUND AND STUDY AIM: Inadequate colorectal cancer screening wastes limited 
      endoscopic resources. We examined patients factors associated with inadequate 
      flexible sigmoidoscopy (FSG) screening at baseline screening and repeat screening 
      3-5 years later in 10 geographically-dispersed screening centers participating in 
      the ongoing Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. 
      METHODS: A total of 64,554 participants (aged 55-74) completed baseline 
      questionnaires and underwent FSG at baseline. Of these, 39,385 participants 
      returned for repeat screening. We used logistic regression models to assess 
      factors that are associated with inadequate FSG (defined as a study in which the 
      depth of insertion of FSG was <50 cm or visual inspection was limited to <90% of 
      the mucosal surface but without detection of a polyp or mass). RESULTS: Of 7084 
      (11%) participants with inadequate FSG at baseline, 6496 (91.7%) had <50 cm depth 
      of insertion (75.3% due to patient discomfort) and 500 (7.1%) participants had 
      adequate depth of insertion but suboptimal bowel preparation. Compared to 55-59 
      year age group, advancing age in 5-year increments (odds ratios (OR) from 1.08 to 
      1.51) and female sex (OR = 2.40; 95% confidence interval (CI): 2.27-2.54) were 
      associated with inadequate FSG. Obesity (BMI > 30 kg/m(2)) was associated with 
      reduced odds (OR = 0.67; 95% CI: 0.62-0.72). Inadequate FSG screening at baseline 
      was associated with inadequate FSG at repeat screening (OR = 6.24; 95% CI: 
      5.78-6.75). CONCLUSIONS: Sedation should be considered for patients with 
      inadequate FSG or an alternative colorectal cancer screening method should be 
      recommended.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Laiyemo, Adeyinka O
AU  - Laiyemo AO
AD  - Division of Gastroenterology, Department of Medicine, Howard University College 
      of Medicine, Washington, DC 20060, USA. adeyinka.laiyemo@howard.edu
FAU - Doubeni, Chyke
AU  - Doubeni C
FAU - Pinsky, Paul F
AU  - Pinsky PF
FAU - Doria-Rose, V Paul
AU  - Doria-Rose VP
FAU - Sanderson, Andrew K 2nd
AU  - Sanderson AK 2nd
FAU - Bresalier, Robert
AU  - Bresalier R
FAU - Weissfeld, Joel
AU  - Weissfeld J
FAU - Schoen, Robert E
AU  - Schoen RE
FAU - Marcus, Pamela M
AU  - Marcus PM
FAU - Prorok, Philip C
AU  - Prorok PC
FAU - Berg, Christine D
AU  - Berg CD
LA  - eng
GR  - 5U54CA091431-09 S1/CA/NCI NIH HHS/United States
GR  - U54 CA091431/CA/NCI NIH HHS/United States
GR  - K01 CA127118/CA/NCI NIH HHS/United States
GR  - Z99 CA999999/Intramural NIH HHS/United States
GR  - 5K01CA127118-03/CA/NCI NIH HHS/United States
GR  - U54 CA091431-01/CA/NCI NIH HHS/United States
GR  - U01 CA151736/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
DEP - 20111122
PL  - Netherlands
TA  - Cancer Epidemiol
JT  - Cancer epidemiology
JID - 101508793
SB  - IM
MH  - Aged
MH  - Colorectal Neoplasms/*diagnosis
MH  - Early Detection of Cancer/methods/*standards
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Sigmoidoscopy/methods/*standards
MH  - United States
PMC - PMC3288883
MID - NIHMS337006
COIS- CONFLICT OF INTEREST We have no conflict of interest to declare
EDAT- 2011/11/25 06:00
MHDA- 2012/10/30 06:00
PMCR- 2013/08/01
CRDT- 2011/11/25 06:00
PHST- 2011/06/21 00:00 [received]
PHST- 2011/10/27 00:00 [revised]
PHST- 2011/10/30 00:00 [accepted]
PHST- 2011/11/25 06:00 [entrez]
PHST- 2011/11/25 06:00 [pubmed]
PHST- 2012/10/30 06:00 [medline]
PHST- 2013/08/01 00:00 [pmc-release]
AID - S1877-7821(11)00172-X [pii]
AID - 10.1016/j.canep.2011.10.013 [doi]
PST - ppublish
SO  - Cancer Epidemiol. 2012 Aug;36(4):395-9. doi: 10.1016/j.canep.2011.10.013. Epub 
      2011 Nov 22.