PMID- 22117409
OWN - NLM
STAT- MEDLINE
DCOM- 20111214
LR  - 20111128
IS  - 0016-6758 (Print)
IS  - 0016-6758 (Linking)
VI  - 47
IP  - 9
DP  - 2011 Sep
TI  - [Comparative FISH analysis of C-positive regions of chromosomes of wood mice 
      (Rodentia, Muridae, Sylvaemus)].
PG  - 1236-46
AB  - The homology of DNA of C-positive centromeric regions of chromosomes in wood mice 
      of the genus Sylvaemus (S. uralensis, S. fulvipectus, S. sylvaticus, S. 
      flavicollis, and S. ponticus) was estimated for the first time. DNA probes were 
      generated by microdissection from the centromeric regions of individual autosomes 
      of each species, and their fluorescence in situ hybridization (FISH) with 
      metaphase chromosomes of representatives of all studied wood mouse species was 
      carried out. Unlike in the chromosomal forms and races of S. uralensis, changes 
      in the DNA composition of the chromosomal centromeric regions in the wood mouse 
      species of the genus Sylvaemus (including closely related S. flavicollis and S. 
      ponticus) are both quantitative and qualitative. The patterns of FISH signals 
      after in situ hybridization of the microdissection DNA probes with chromosomes of 
      the species involved in the study demonstrate significant differences between 
      C-positive regions of wood mouse chromosomes in the copy number and the level of 
      homology of repetitive sequences as well as in the localization of homologous 
      repetitive sequences. It was shown that C-positive regions of wood mouse 
      chromosomes can contain both homologous and distinct sets of repetitive 
      sequences. Regions enriched with homologous repeats were detected either directly 
      in C-positive regions of individual chromosomes or only on the short arms of 
      acrocentrics, or at the boundary of C-positive and C-negative regions.
FAU - Rubtsov, N B
AU  - Rubtsov NB
FAU - Karamysheva, T V
AU  - Karamysheva TV
FAU - Bogdanov, A S
AU  - Bogdanov AS
FAU - Likhoshvai, T V
AU  - Likhoshvai TV
FAU - Kartavtseva, I V
AU  - Kartavtseva IV
LA  - rus
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Russia (Federation)
TA  - Genetika
JT  - Genetika
JID - 0047354
SB  - IM
MH  - Animals
MH  - Centromere/*genetics
MH  - *Chromosome Painting
MH  - Chromosomes, Mammalian/*genetics
MH  - Muridae/*genetics
MH  - Species Specificity
EDAT- 2011/11/29 06:00
MHDA- 2011/12/15 06:00
CRDT- 2011/11/29 06:00
PHST- 2011/11/29 06:00 [entrez]
PHST- 2011/11/29 06:00 [pubmed]
PHST- 2011/12/15 06:00 [medline]
PST - ppublish
SO  - Genetika. 2011 Sep;47(9):1236-46.