PMID- 22120029 OWN - NLM STAT- MEDLINE DCOM- 20120320 LR - 20161125 IS - 1074-9357 (Print) IS - 1074-9357 (Linking) VI - 18 Suppl 1 DP - 2011 Oct TI - Estimating the minimal clinically important difference of an upper extremity recovery measure in subacute stroke patients. PG - 599-610 LID - 10.1310/tsr18s01-599 [doi] AB - BACKGROUND: The minimal clinically important difference (MCID) estimates of some of the stroke-related measures are available; but MCID of the Fugl-Meyer assessment (FMA) measure is unknown, which limits the application and interpretation of change scores in poststroke patients with motor deficits. OBJECTIVE: To estimate the MCID of the FMA-UE (upper extremity) using the modified Rankin scale (mRS) and global rating of patient-perceived changes (GRPPC) in subacute poststroke patients. METHODS: The prospective, cohort study took place in the neurology department of a university hospital. Seventy-one subacute poststroke (mean duration, 8.42 weeks) patients were prospectively enrolled in a randomized clinical trial of the ongoing Meaningful Task Specific Training (MTST). FMA-UE, mRS, and GRPPC scores were obtained at pre- and 4 weeks postintervention. RESULTS: The MCID values of FMA-UE were 9 (80.39% sensitive and 70% specific) and 10 (97.62% sensitive and 89.66% specific) anchored to mRS and GRPPC, respectively. CONCLUSIONS: The estimated MCID score for the upper extremity motor recovery among patients with subacute stroke is 9 to 10 on the FMA-UE. Patients with subacute stroke who achieve a score of 9 to 10 on FMA-UE are more likely to experience or perceive a meaningful and clinically important improvement in their disability level than those who do not. The reference value can be used to develop goals and interpret progress in subacute poststroke patients. FAU - Arya, Kamal Narayan AU - Arya KN AD - Department of Neurology, CSM Medical University, Lucknow, India. FAU - Verma, Rajesh AU - Verma R FAU - Garg, R K AU - Garg RK LA - eng PT - Journal Article PT - Randomized Controlled Trial PL - England TA - Top Stroke Rehabil JT - Topics in stroke rehabilitation JID - 9439750 SB - IM MH - Adult MH - Aged MH - Arm/physiology MH - Confidence Intervals MH - Data Interpretation, Statistical MH - Female MH - Humans MH - Likelihood Functions MH - Male MH - Middle Aged MH - Movement/physiology MH - Neuropsychological Tests MH - Prospective Studies MH - ROC Curve MH - Recovery of Function/*physiology MH - Stroke/physiopathology MH - *Stroke Rehabilitation MH - Upper Extremity/*physiology EDAT- 2011/11/29 06:00 MHDA- 2012/03/21 06:00 CRDT- 2011/11/29 06:00 PHST- 2011/11/29 06:00 [entrez] PHST- 2011/11/29 06:00 [pubmed] PHST- 2012/03/21 06:00 [medline] AID - J03617H495L57624 [pii] AID - 10.1310/tsr18s01-599 [doi] PST - ppublish SO - Top Stroke Rehabil. 2011 Oct;18 Suppl 1:599-610. doi: 10.1310/tsr18s01-599.