PMID- 22120681
OWN - NLM
STAT- MEDLINE
DCOM- 20120604
LR  - 20120131
IS  - 1873-6246 (Electronic)
IS  - 0301-0511 (Linking)
VI  - 89
IP  - 2
DP  - 2012 Feb
TI  - The effects of aging on lifetime of auditory sensory memory in humans.
PG  - 306-12
LID - 10.1016/j.biopsycho.2011.11.003 [doi]
AB  - The amplitude change of cortical responses to repeated stimulation with respect 
      to different interstimulus intervals (ISIs) is considered as an index of sensory 
      memory. To determine the effect of aging on lifetime of auditory sensory memory, 
      N100m responses were recorded in young, middle-aged, and elderly healthy 
      volunteers (n=15 for each group). Trains of 5 successive tones were presented 
      with an inter-train interval of 10 s. In separate sessions, the within-train ISIs 
      were 0.5, 1, 2, 4, and 8 s. The amplitude ratio between N100m responses to the 
      first and fifth stimuli (S5/S1 N100m ratio) within each ISI condition was 
      obtained to reflect the recovery cycle profile. The recovery function time 
      constant (tau) was smaller in the elderly (1.06+/-0.26 s, p<0.001) and middle-aged 
      (1.70+/-0.25 s, p=0.009) groups compared with the young group (2.77+/-0.25 s). In 
      conclusion, the present study suggests an aging-related decrease in lifetime of 
      auditory sensory memory.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Cheng, Chia-Hsiung
AU  - Cheng CH
AD  - Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan.
FAU - Lin, Yung-Yang
AU  - Lin YY
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111124
PL  - Netherlands
TA  - Biol Psychol
JT  - Biological psychology
JID - 0375566
SB  - IM
MH  - Acoustic Stimulation
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aging/*physiology
MH  - Brain Mapping
MH  - Cerebral Cortex/*physiology
MH  - Evoked Potentials, Auditory/*physiology
MH  - Female
MH  - Hearing/*physiology
MH  - Humans
MH  - Magnetoencephalography
MH  - Male
MH  - Memory/*physiology
MH  - Middle Aged
MH  - Reaction Time/physiology
EDAT- 2011/11/29 06:00
MHDA- 2012/06/05 06:00
CRDT- 2011/11/29 06:00
PHST- 2011/04/01 00:00 [received]
PHST- 2011/11/07 00:00 [revised]
PHST- 2011/11/12 00:00 [accepted]
PHST- 2011/11/29 06:00 [entrez]
PHST- 2011/11/29 06:00 [pubmed]
PHST- 2012/06/05 06:00 [medline]
AID - S0301-0511(11)00287-0 [pii]
AID - 10.1016/j.biopsycho.2011.11.003 [doi]
PST - ppublish
SO  - Biol Psychol. 2012 Feb;89(2):306-12. doi: 10.1016/j.biopsycho.2011.11.003. Epub 
      2011 Nov 24.