PMID- 22128311
OWN - NLM
STAT- MEDLINE
DCOM- 20120302
LR  - 20111130
IS  - 0025-0244 (Print)
IS  - 0025-0244 (Linking)
VI  - 55
IP  - 4
DP  - 2011 Nov
TI  - [The effect of different patient positions on overlapping volumes in radiotherapy 
      of patients with high-risk prostate cancer].
PG  - 281-5
AB  - The purpose of the study was to evaluate the relationship among planning target 
      volumes (PTVs) and organs at risk (OARs) based on four different radiotherapy 
      treatment plans for high-risk prostate cancer patients. CT scans were obtained in 
      supine position with knee and ankle support (KAS) and in prone position with 
      belly-board (BB) both with full bladder (FB) and empty bladder (EB). Overlapping 
      volumes of the delineated PTVs and OARs on four different setup combinations 
      (KAS-FB; BB-FB; KAS-EB; BB-EB) were analyzed according to the patient position, 
      bladder filling and circumference of abdomen (CA). Overlapping ( intersection) was 
      significantly smaller with FB than with EB at the bowels and bladder: 
      PTVpel intersectionbladder: p=0.0069, PTVpvs intersectionbladder: p<0.001, PTVp intersectionbladder: p<0.001, 
      PTVpel intersectionbowels: p=0.0055. Comparison according to small and large CA resulted in 
      significantly smaller overlapping of PTVs and OARs for large CA patients at: 
      KAS-FB: PTVpel intersectionrectum: p=0.0255, PTVpvs intersectionrectum: p=0.0179, PTVp intersectionrectum: p=0.0386, 
      PTVpel intersectionbladder: p=0.0355. KAS-EB: PTVpvs intersectionbladder: p=0.0184, PTVp intersectionbladder: 
      p=0.0107. BB-EB: PTVpvs intersectionbladder: p=0.0464, PTVp intersectionbladder: p=0.0077. The exception 
      was PTVpel intersectionrectum at KAS-FB where the overlapping were smaller for small CA 
      (p=0.0255). According to our results we recommend to deliver radiotherapy 
      treatment for high-risk prostate cancer patients in supine position with KAS 
      immobilization and full bladder. The overlapping volumes of PTVs and OARs were 
      smaller practically at all patients with larger circumference of abdomen.
FAU - Czigner, Krisztina
AU  - Czigner K
AD  - Sugarterapias Osztaly, Orszagos Onkologiai Intezet, Budapest, Hungary. 
      kczigner7@yahoo.com
FAU - Agoston, Peter
AU  - Agoston P
FAU - Forgacs, Gyula
AU  - Forgacs G
FAU - Kasler, Miklos
AU  - Kasler M
LA  - hun
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - A betegfektetes hatasa a vedendo szervek es a celterfogatok atfedesere nagy 
      kockazatu prosztatarakos betegek sugarkezelesekor.
DEP - 20110717
PL  - Hungary
TA  - Magy Onkol
JT  - Magyar onkologia
JID - 9313833
SB  - IM
MH  - Aged
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prostatic Neoplasms/*radiotherapy
MH  - Radiotherapy Dosage
MH  - *Radiotherapy Planning, Computer-Assisted
MH  - Radiotherapy, Computer-Assisted/adverse effects/*methods
MH  - Rectum/*radiation effects
MH  - *Supine Position
MH  - Urinary Bladder/*radiation effects
MH  - Urine
EDAT- 2011/12/01 06:00
MHDA- 2012/03/03 06:00
CRDT- 2011/12/01 06:00
PHST- 2011/05/02 00:00 [received]
PHST- 2011/07/17 00:00 [accepted]
PHST- 2011/12/01 06:00 [entrez]
PHST- 2011/12/01 06:00 [pubmed]
PHST- 2012/03/03 06:00 [medline]
PST - ppublish
SO  - Magy Onkol. 2011 Nov;55(4):281-5. Epub 2011 Jul 17.