PMID- 22128738
OWN - NLM
STAT- MEDLINE
DCOM- 20120906
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 8
DP  - 2011 Aug
TI  - [Determination of imidocarb residue in swine tissues by high performance liquid 
      chromatography].
PG  - 750-4
AB  - A quantitive method for the determination of imidocarb residue in edible tissues 
      of swine by high performance liquid chromatography (HPLC) was developed. The 
      analyte was digested by beta-glucosidase first, and then extracted with 1 mol/L 
      hydrochloric acid. The aqueous phase was back-extracted with the mixture of 
      hexane-isoamyl alcohol (3: 2, v/v) for the purification. The mobile phases were 
      acetonitrile (phase A) and 0.007 5 mol/L 1-pentansulfonic acid sodium aqueous 
      solution containing 0.1% triethylamine, adjusted to pH 3.0 with glacial acetic 
      acid (phase B). The analyte was detected by ultraviolet absorption spectroscopy 
      after the separation was achieved on a C18 RP column. The linear range was 10 - 
      10 000 micog/L, and the correlation coefficient was more than 0.999. The limit of 
      detection (LOD) was 10 microg/kg, and the limit of qualification (LOQ) was 20 
      microg/kg. The mean recoveries of imidocarb in swine tissues at the added levels 
      of LOQ, MRL (maximum residue limit) and 2MRL ranged from 80.04% to 110.32%, and 
      the relative standard deviations (RSDs) of intra- and inter-day analyses ranged 
      from 0.82% to 10.00%. The method is simple and sensitive for the quantification 
      of imidocarb residue in swine tissues.
FAU - Yu, Huimin
AU  - Yu H
AD  - National Reference Laboratory of Veterinary Drug Residues (SCAU), South China 
      Agricultural University, Guangzhou 510642, China.
FAU - Huang, Xianhui
AU  - Huang X
FAU - Zhong, Jialin
AU  - Zhong J
FAU - Yang, Gang
AU  - Yang G
FAU - Fang, Qiuhua
AU  - Fang Q
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Antiprotozoal Agents)
RN  - 8USS3K0VDH (Imidocarb)
SB  - IM
MH  - Adipose Tissue/chemistry
MH  - Animals
MH  - Antiprotozoal Agents/analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Drug Residues/*analysis
MH  - Food Contamination/*analysis
MH  - Imidocarb/*analysis
MH  - Liver/chemistry
MH  - Meat/*analysis
MH  - Swine
EDAT- 2011/12/02 06:00
MHDA- 2012/09/07 06:00
CRDT- 2011/12/02 06:00
PHST- 2011/12/02 06:00 [entrez]
PHST- 2011/12/02 06:00 [pubmed]
PHST- 2012/09/07 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2011 Aug;29(8):750-4.