PMID- 22128893
OWN - NLM
STAT- MEDLINE
DCOM- 20121119
LR  - 20181201
IS  - 1365-3156 (Electronic)
IS  - 1360-2276 (Linking)
VI  - 17
IP  - 3
DP  - 2012 Mar
TI  - Acceptability of coupling intermittent preventive treatment in infants with the 
      expanded programme on immunization in three francophone countries in Africa.
PG  - 308-15
LID - 10.1111/j.1365-3156.2011.02915.x [doi]
AB  - OBJECTIVE: Intermittent preventive treatment in infants (IPTi) is a malaria 
      control strategy currently recommended by WHO for implementation at scale in 
      Africa, consisting of administration of sulphadoxine-pyrimethamine (SP) coupled 
      with routine immunizations offered to children under 1 year. In this study, we 
      analysed IPTi acceptability by communities and health staff. METHODS: Direct 
      observation, in-depth interviews (IDIs) and focus group discussions (FGDs) were 
      conducted in Benin, Madagascar and Senegal during IPTi pilot implementation. 
      Villages were stratified by immunization coverage. Data were transcribed and 
      analysed using NVivo7 software. RESULTS: Communities' knowledge of malaria 
      aetiology and diagnosis was good, although generally villagers did not seek 
      treatment at health centres as their first choice. Perceptions and attitudes 
      towards IPTi were very positive among communities and health workers. A 
      misconception that SP was an antipyretic that prevents post-vaccinal fever 
      contributed to IPTi's acceptability. No refusals or negative rumours related to 
      IPTi coupling with immunizations were identified, and IPTi did not negatively 
      influence attitudes towards other malaria control strategies. Healthcare 
      decisions about children, normatively made by the father, are starting to shift 
      to educated and financially independent mothers. DISCUSSION: Intermittent 
      preventive treatment in infants is well accepted by providers and communities, 
      showing a synergic acceptability when coupled with routine immunizations. 
      However, a misconception that SP alleviates fever should be addressed when 
      scaling up implementation.
CI  - (c) 2011 Blackwell Publishing Ltd.
FAU - de Sousa, Alexandra
AU  - de Sousa A
AD  - World Health Organization, Geneva, Switzerland. desousaa@who.int
FAU - Rabarijaona, Leon P
AU  - Rabarijaona LP
FAU - Ndiaye, Jean L
AU  - Ndiaye JL
FAU - Sow, Doudou
AU  - Sow D
FAU - Ndyiae, Mouhamed
AU  - Ndyiae M
FAU - Hassan, Jacques
AU  - Hassan J
FAU - Lambo, Nilda
AU  - Lambo N
FAU - Adovohekpe, Paul
AU  - Adovohekpe P
FAU - Guidetti, Flavia
AU  - Guidetti F
FAU - Recht, Judith
AU  - Recht J
FAU - Affo, Alphonse
AU  - Affo A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111129
PL  - England
TA  - Trop Med Int Health
JT  - Tropical medicine & international health : TM & IH
JID - 9610576
RN  - 0 (Antimalarials)
RN  - 0 (Antipyretics)
RN  - 0 (Bacterial Vaccines)
RN  - 0 (Drug Combinations)
RN  - 0 (Measles Vaccine)
RN  - 37338-39-9 (fanasil, pyrimethamine drug combination)
RN  - 88463U4SM5 (Sulfadoxine)
RN  - Z3614QOX8W (Pyrimethamine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Antimalarials/administration & dosage/*therapeutic use
MH  - Antipyretics
MH  - *Attitude of Health Personnel
MH  - Bacterial Vaccines
MH  - Benin
MH  - Community Health Services/statistics & numerical data
MH  - Decision Making
MH  - Drug Combinations
MH  - Female
MH  - *Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - *Immunization Programs
MH  - Infant
MH  - Madagascar
MH  - Malaria/*prevention & control
MH  - Male
MH  - Measles Vaccine
MH  - Middle Aged
MH  - Parents
MH  - *Patient Acceptance of Health Care
MH  - Perception
MH  - Pyrimethamine/administration & dosage/*therapeutic use
MH  - Residence Characteristics
MH  - Senegal
MH  - Sulfadoxine/administration & dosage/*therapeutic use
MH  - Vaccination
MH  - World Health Organization
MH  - Young Adult
EDAT- 2011/12/02 06:00
MHDA- 2012/12/10 06:00
CRDT- 2011/12/02 06:00
PHST- 2011/12/02 06:00 [entrez]
PHST- 2011/12/02 06:00 [pubmed]
PHST- 2012/12/10 06:00 [medline]
AID - 10.1111/j.1365-3156.2011.02915.x [doi]
PST - ppublish
SO  - Trop Med Int Health. 2012 Mar;17(3):308-15. doi: 
      10.1111/j.1365-3156.2011.02915.x. Epub 2011 Nov 29.