PMID- 22129006 OWN - NLM STAT- MEDLINE DCOM- 20120328 LR - 20111201 IS - 1089-7623 (Electronic) IS - 0034-6748 (Linking) VI - 82 IP - 11 DP - 2011 Nov TI - Micromachined fragment capturer for biomedical applications. PG - 115004 LID - 10.1063/1.3662471 [doi] AB - Due to changes in modern diet, a form of heart disease called chronic total occlusion has become a serious disease to be treated as an emergency. In this study, we propose a micromachined capturer that is designed and fabricated to collect plaque fragments generated during surgery to remove the thrombus. The fragment capturer consists of a plastic body made by rapid prototyping, SU-8 mesh structures using MEMS techniques, and ionic polymer metal composite (IPMC) actuators. An array of IPMC actuators combined with the SU-8 net structure was optimized to effectively collect plaque fragments. The evaporation of solvent through the actuator's surface was prevented using a coating of SU-8 and polydimethylsiloxane thin film on the actuator. This approach improved the available operating time of the IPMC, which primarily depends on solvent loss. Our preliminary results demonstrate the possibility of using the capturer for biomedical applications. CI - (c) 2011 American Institute of Physics FAU - Choi, Young-Soo AU - Choi YS AD - MEMS and Nanotechnology Laboratory, School of Mechanical Systems Engineering, Chonnam National University, 300 Yongbong, Buk, Gwangju 500-757, South Korea. FAU - Lee, Dong-Weon AU - Lee DW LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Rev Sci Instrum JT - The Review of scientific instruments JID - 0405571 RN - 0 (Dimethylpolysiloxanes) RN - 0 (Epoxy Compounds) RN - 0 (Polymers) RN - 0 (SU-8 compound) RN - 63148-62-9 (baysilon) SB - IM MH - Dimethylpolysiloxanes/chemistry MH - Electrodes MH - Epoxy Compounds/chemistry MH - Microtechnology/*instrumentation MH - Polymers/chemistry MH - Surface Properties MH - Thrombosis/surgery MH - Vascular Surgical Procedures/*instrumentation EDAT- 2011/12/02 06:00 MHDA- 2012/03/29 06:00 CRDT- 2011/12/02 06:00 PHST- 2011/12/02 06:00 [entrez] PHST- 2011/12/02 06:00 [pubmed] PHST- 2012/03/29 06:00 [medline] AID - 10.1063/1.3662471 [doi] PST - ppublish SO - Rev Sci Instrum. 2011 Nov;82(11):115004. doi: 10.1063/1.3662471.