PMID- 22138227
OWN - NLM
STAT- MEDLINE
DCOM- 20120222
LR  - 20151119
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1219
DP  - 2012 Jan 6
TI  - Monolithic molecular imprinted polymer fiber for recognition and solid phase 
      microextraction of ephedrine and pseudoephedrine in biological samples prior to 
      capillary electrophoresis analysis.
PG  - 195-200
LID - 10.1016/j.chroma.2011.11.016 [doi]
AB  - A novel capillary electrophoresis (CE) method coupled with monolithic molecular 
      imprinted polymer (MIP) fiber based solid phase microextraction (SPME) was 
      developed for selective and sensitive determination of ephedrine (E) and 
      pseudoephedrine (PE). With in situ polymerization in a silica capillary mold and 
      E as template, the MIP fibers could be produced in batch reproducibly and each 
      fiber was available for 50 extraction cycles without significant decrease in 
      extraction ability. Using the MIP fiber under optimized extraction conditions, CE 
      detection limits of E and PE were greatly lowered from 0.20 to 0.00096 mug/mL and 
      0.12 to 0.0011 mug/mL, respectively. Analysis of urine and serum samples by the 
      MIP-SPME-CE method was also performed, with results indicating that E and PE 
      could be selectively extracted. The recoveries and relative standard deviations 
      (RSDs) for sample analysis were found in the range of 91-104% and 3.8-9.1%, 
      respectively.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Deng, Dong-Li
AU  - Deng DL
AD  - Analytical & Testing Center, Sichuan University, Chengdu, China.
FAU - Zhang, Ji-You
AU  - Zhang JY
FAU - Chen, Chen
AU  - Chen C
FAU - Hou, Xiao-Ling
AU  - Hou XL
FAU - Su, Ying-Ying
AU  - Su YY
FAU - Wu, Lan
AU  - Wu L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111115
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 451W47IQ8X (Sodium Chloride)
RN  - 7CUC9DDI9F (Pseudoephedrine)
RN  - GN83C131XS (Ephedrine)
RN  - Q40Q9N063P (Acetic Acid)
RN  - Y4S76JWI15 (Methanol)
SB  - IM
MH  - Acetic Acid
MH  - Electrophoresis, Capillary/*methods
MH  - Ephedrine/blood/*isolation & purification/urine
MH  - Humans
MH  - Limit of Detection
MH  - Methanol
MH  - Molecular Imprinting/*methods
MH  - Pseudoephedrine/blood/*isolation & purification/urine
MH  - Reproducibility of Results
MH  - Sodium Chloride
MH  - Solid Phase Microextraction/instrumentation/*methods
MH  - Time Factors
EDAT- 2011/12/06 06:00
MHDA- 2012/02/23 06:00
CRDT- 2011/12/06 06:00
PHST- 2011/08/04 00:00 [received]
PHST- 2011/11/01 00:00 [revised]
PHST- 2011/11/08 00:00 [accepted]
PHST- 2011/12/06 06:00 [entrez]
PHST- 2011/12/06 06:00 [pubmed]
PHST- 2012/02/23 06:00 [medline]
AID - S0021-9673(11)01683-9 [pii]
AID - 10.1016/j.chroma.2011.11.016 [doi]
PST - ppublish
SO  - J Chromatogr A. 2012 Jan 6;1219:195-200. doi: 10.1016/j.chroma.2011.11.016. Epub 
      2011 Nov 15.