PMID- 22145346 OWN - NLM STAT- MEDLINE DCOM- 20120105 LR - 20201209 IS - 0372-9311 (Print) IS - 0372-9311 (Linking) IP - 5 DP - 2011 Sep-Oct TI - [Detection of natural tularemia foci in Mongolia]. PG - 31-6 AB - AIM: Study of the current spread of natural tularemia foci in Mongolia and its epizootic activity evaluation for consequent substantiation of the recommendations for prophylaxis of this disease. MATERIALS AND METHODS: Study of 1119 pellet specimens from predatory birds obtained in 6 aimag in Mongolia in 2008--2010 was performed. Tularemia antigen was detected by using antibody neutralization reaction (ANR) and passive hemagglutination reaction (PHR) with tularemia diagnosticums. Tularemia DNA was detected by PCR by using strain specific primers. Presence of plague antigen in PHR with plague immunoglobulin diagnosticum was also studied in all the samples. RESULTS: Epizootologic monitoring allowed the detection of natural tularemia foci in 5 of the 6 studied aimags in Mongolia. PHR was the most effective study method that allowed to detect tularemia antigen in the environmental objects in high quantities (up to 9.2% of positive samples) and high titers (up to 1:1600). PCR was less effective. Plague antigen was detected in 9 samples in 2010 for the first time, and in 3 cases together with tularemia antigen, which indicates a presence of combined natural foci of tularemia and plague in this territory. CONCLUSION: In the studied regions of Mongolia natural tularemia foci were detected, their epizootic activity was determined and recommendations for future study tactics of natural tularemia foci were given. FAU - Meshcheriakova, I S AU - Meshcheriakova IS FAU - Korenberg, E I AU - Korenberg EI FAU - Tserennorov, D AU - Tserennorov D FAU - Mikhailova, T V AU - Mikhailova TV FAU - Kormilitsyna, M I AU - Kormilitsyna MI FAU - Batjav, D AU - Batjav D FAU - Dagvadorj, Y AU - Dagvadorj Y FAU - Demidova, T N AU - Demidova TN FAU - Otgonbaatar, D AU - Otgonbaatar D FAU - Enkhbold, N AU - Enkhbold N FAU - Mendamar, L AU - Mendamar L LA - rus PT - Journal Article PL - Russia (Federation) TA - Zh Mikrobiol Epidemiol Immunobiol JT - Zhurnal mikrobiologii, epidemiologii i immunobiologii JID - 0415217 RN - 0 (Antibodies) SB - IM MH - Animals MH - Antibodies MH - Birds/microbiology MH - Disease Reservoirs/microbiology MH - Francisella tularensis/*isolation & purification MH - Humans MH - Mongolia/epidemiology MH - Rodentia/microbiology MH - Tularemia/*epidemiology/microbiology EDAT- 2011/12/08 06:00 MHDA- 2012/01/06 06:00 CRDT- 2011/12/08 06:00 PHST- 2011/12/08 06:00 [entrez] PHST- 2011/12/08 06:00 [pubmed] PHST- 2012/01/06 06:00 [medline] PST - ppublish SO - Zh Mikrobiol Epidemiol Immunobiol. 2011 Sep-Oct;(5):31-6.