PMID- 22145374 OWN - NLM STAT- MEDLINE DCOM- 20120125 LR - 20161020 IS - 0869-6047 (Print) IS - 0869-6047 (Linking) IP - 9 DP - 2011 TI - [Analysis of DNA and chromosome damage by the methods of molecular cytogenetics]. PG - 57-63 AB - The main hybrid techniques of molecular cytogenetics are described. Methodological aspects of combination of fluorescence in situ hybridization (FISH) with the comet assay and micronuclei (MN) test are discussed along with results of their application to evaluate and locate DNA and chromosome damage in the genome. The experience of the authors with the application of FISH in combination with the comet assay and MN test are reported. FAU - Arutiunian, R M AU - Arutiunian RM FAU - Oganesian, G G AU - Oganesian GG LA - rus PT - English Abstract PT - Journal Article PL - Russia (Federation) TA - Vestn Ross Akad Med Nauk JT - Vestnik Rossiiskoi akademii meditsinskikh nauk JID - 9215641 RN - 9007-49-2 (DNA) SB - IM MH - *Chromosome Aberrations MH - Chromosomes, Human/metabolism MH - Comet Assay/*methods MH - Cytogenetics/methods MH - DNA/analysis MH - *DNA Damage MH - Humans MH - In Situ Hybridization, Fluorescence/*methods MH - Micronucleus Tests/*methods MH - Mutagenesis EDAT- 2011/12/08 06:00 MHDA- 2012/01/26 06:00 CRDT- 2011/12/08 06:00 PHST- 2011/12/08 06:00 [entrez] PHST- 2011/12/08 06:00 [pubmed] PHST- 2012/01/26 06:00 [medline] PST - ppublish SO - Vestn Ross Akad Med Nauk. 2011;(9):57-63.