PMID- 22157984 OWN - NLM STAT- MEDLINE DCOM- 20121221 LR - 20220311 IS - 1745-7262 (Electronic) IS - 1008-682X (Print) IS - 1008-682X (Linking) VI - 14 IP - 4 DP - 2012 Jul TI - Is there a correlation between the outcome of transurethral resection of prostate and preoperative degree of bladder outlet obstruction? PG - 556-9 LID - 10.1038/aja.2011.157 [doi] AB - To compare the impact of transurethral resection of prostate (TURP) on symptom scores and maximal flow rates (Qmax) in patients with equivocal bladder outlet obstruction (BOO) and definite BOO and to assess the relationship between the surgical outcomes and degree of preoperative BOO, we prospectively evaluated men with lower urinary tract symptoms and bladder outlet obstruction index (BOOI) greater than 20, who were refractory to conventional medical treatment and underwent TURP. Urodynamic evaluation, International Prostate Symptom Score (IPSS), uroflowmetry, post-void residual volume (PVR) check and transrectal ultrasound were performed. 20/=40 as definite BOO. Changes of IPSS, Qmax, PVR and correlation analysis was performed between the degree of improvement of Qmax, subdomains of IPSS and BOOI. Fifty-four patients showed equivocal BOO and 80 patients showed definite BOO. Preoperatively equivocal BOO group and definite BOO group showed significant differences in maximal bladder capacity and prevalence of detrusor overactivity, whereas no difference was noted in prostate volume. Postoperatively both groups showed improvements in Qmax, obstructive (IPSSO) and irritative (IPSSI) subdomain of IPSS, but the degree of improvement in Qmax and IPSSI subdomain was statistically significantly greater in definite BOO group. The degree of improvement of Qmax and IPSSI showed weak correlation with preoperative BOOI. As a weak correlation was identified between preoperative degree of BOO and outcome of TURP, other factors other than BOOI such as severity of patients' symptoms should be considered in deciding treatment modality. FAU - Oh, Mi Mi AU - Oh MM AD - Department of Urology, Korea University Medical Center, Seoul 435-766, Korea. FAU - Kim, Jin Wook AU - Kim JW FAU - Kim, Je Jong AU - Kim JJ FAU - Moon, Du Geon AU - Moon du G LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20111212 PL - China TA - Asian J Androl JT - Asian journal of andrology JID - 100942132 SB - IM MH - Aged MH - Humans MH - Male MH - Middle Aged MH - Organ Size MH - Preoperative Period MH - Prostatic Hyperplasia/complications/*pathology/*surgery MH - Prostatism/etiology MH - Severity of Illness Index MH - *Transurethral Resection of Prostate MH - Treatment Outcome MH - Urinary Bladder Neck Obstruction/etiology/*pathology MH - Urinary Bladder, Overactive/etiology MH - Urodynamics PMC - PMC3720082 EDAT- 2011/12/14 06:00 MHDA- 2012/12/22 06:00 PMCR- 2012/07/01 CRDT- 2011/12/14 06:00 PHST- 2011/12/14 06:00 [entrez] PHST- 2011/12/14 06:00 [pubmed] PHST- 2012/12/22 06:00 [medline] PHST- 2012/07/01 00:00 [pmc-release] AID - aja2011157 [pii] AID - 10.1038/aja.2011.157 [doi] PST - ppublish SO - Asian J Androl. 2012 Jul;14(4):556-9. doi: 10.1038/aja.2011.157. Epub 2011 Dec 12.