PMID- 22158608 OWN - NLM STAT- MEDLINE DCOM- 20120207 LR - 20200522 IS - 1523-1747 (Electronic) IS - 0022-202X (Linking) VI - 132 IP - 1 DP - 2012 Jan TI - Targeting skin: vitiligo and autoimmunity. PG - 13-5 LID - 10.1038/jid.2011.353 [doi] AB - In this issue, Singh and co-workers describe the results of classical typing of human leukocyte antigen (HLA) alleles in 1,404 vitiligo patients and 902 unaffected controls from North India and follow-up HLA typing in 355 cases and 441 controls from Gujarat. The increased frequency of DRB1*07:01 in North Indian and Gujarat populations with generalized and localized vitiligo and in several vitiligo populations studied previously suggests that it contributes to autoimmunity and destruction of melanocytes. FAU - Bowcock, Anne M AU - Bowcock AM AD - Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA. bowcock@genetics.wustl.edu FAU - Fernandez-Vina, Marcelo AU - Fernandez-Vina M LA - eng PT - Comment PT - Journal Article PL - United States TA - J Invest Dermatol JT - The Journal of investigative dermatology JID - 0426720 RN - 0 (HLA-A Antigens) RN - 0 (HLA-A*36:01 antigen) RN - 0 (HLA-B44 Antigen) RN - 0 (HLA-DRB1 Chains) RN - 0 (HLA-DRB1*07 antigen) SB - IM CON - J Invest Dermatol. 2012 Jan;132(1):124-34. PMID: 21833019 MH - Female MH - HLA-A Antigens/*genetics MH - HLA-B44 Antigen/*genetics MH - HLA-DRB1 Chains/*genetics MH - Humans MH - Male MH - Vitiligo/*genetics/*immunology EDAT- 2011/12/14 06:00 MHDA- 2012/02/09 06:00 CRDT- 2011/12/14 06:00 PHST- 2011/12/14 06:00 [entrez] PHST- 2011/12/14 06:00 [pubmed] PHST- 2012/02/09 06:00 [medline] AID - S0022-202X(15)35452-X [pii] AID - 10.1038/jid.2011.353 [doi] PST - ppublish SO - J Invest Dermatol. 2012 Jan;132(1):13-5. doi: 10.1038/jid.2011.353.