PMID- 22162488
OWN - NLM
STAT- MEDLINE
DCOM- 20151026
LR  - 20191210
IS  - 1615-9314 (Electronic)
IS  - 1615-9306 (Linking)
VI  - 35
IP  - 2
DP  - 2012 Jan
TI  - Enantioselective determination of triazole fungicide tebuconazole in vegetables, 
      fruits, soil and water by chiral liquid chromatography/tandem mass spectrometry.
PG  - 206-15
LID - 10.1002/jssc.201100674 [doi]
AB  - A novel and sensitive method was developed for the determination of tebuconazole 
      enantioselectively using reversed-phase LC-MS/MS. The separation and 
      determination were performed using on an amylose-based chiral stationary phase, a 
      Lux 3u Amylose-2 column (150 mmx2.0 mm), under isocratic conditions at 0.3 mL/min 
      flow rate. A series of chiral stationary phases were investigated and the effect 
      of mobile phase composition on the enantioseparation was discussed. Parameters 
      including the matrix effect, linearity, precision, accuracy and stability were 
      evaluated. Under optimal conditions, the overall mean recoveries for two 
      enantiomers from the soil, tomato, cucumber, pear and apple samples were 
      79.3-101.1% with 2.8-11.5% intra-day relative standard deviations (RSDs) and 
      4.1-8.6% inter-day RSDs at 5, 25 and 50 mug/kg levels; the mean enantiomer 
      recoveries from the water samples were 89.6-101.9% with 3.3-10.2% intra-day RSDs 
      and 5.1-7.7% inter-day RSDs at 0.25, 0.5 and 2.5 mug/kg levels. The limits of 
      detection (LODs) for all enantiomers in tomato, cucumber, pear, apple, soil and 
      water were less than 0.6 mug/kg, whereas the limit of quantification (LOQ) did not 
      exceed 2.0 mug/kg. The results indicate that this proposed method is convenient 
      and reliable for the enantioselective determination of tebuconazole enantiomers 
      in foods and environment samples.
CI  - Copyright (c) 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
FAU - Li, Yuanbo
AU  - Li Y
AD  - Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key 
      Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 
      Beijing, P. R. China. yongquan_zheng@yahoo.com.cn
FAU - Dong, Fengshou
AU  - Dong F
FAU - Liu, Xingang
AU  - Liu X
FAU - Xu, Jun
AU  - Xu J
FAU - Li, Jing
AU  - Li J
FAU - Kong, Zhiqiang
AU  - Kong Z
FAU - Chen, Xiu
AU  - Chen X
FAU - Zheng, Yongquan
AU  - Zheng Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20111212
PL  - Germany
TA  - J Sep Sci
JT  - Journal of separation science
JID - 101088554
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Soil Pollutants)
RN  - 0 (Triazoles)
RN  - 0 (Water Pollutants, Chemical)
RN  - 401ATW8TRW (tebuconazole)
SB  - IM
MH  - Chromatography, Liquid/*methods
MH  - Food Contamination/analysis
MH  - Fruit/chemistry
MH  - Fungicides, Industrial/*analysis/*chemistry
MH  - Humans
MH  - Limit of Detection
MH  - Soil Pollutants/analysis
MH  - Stereoisomerism
MH  - Tandem Mass Spectrometry/*methods
MH  - Triazoles/*analysis/*chemistry
MH  - Vegetables/chemistry
MH  - Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Chirality
OT  - Enantiomers
OT  - Enantioselectivity
OT  - LC-MS/MS
OT  - Tebuconazole
EDAT- 2011/12/14 06:00
MHDA- 2015/10/27 06:00
CRDT- 2011/12/14 06:00
PHST- 2011/07/29 00:00 [received]
PHST- 2011/10/02 00:00 [revised]
PHST- 2011/10/24 00:00 [accepted]
PHST- 2011/12/14 06:00 [entrez]
PHST- 2011/12/14 06:00 [pubmed]
PHST- 2015/10/27 06:00 [medline]
AID - 10.1002/jssc.201100674 [doi]
PST - ppublish
SO  - J Sep Sci. 2012 Jan;35(2):206-15. doi: 10.1002/jssc.201100674. Epub 2011 Dec 12.