PMID- 22164171
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20120823
LR  - 20211021
IS  - 1687-921X (Electronic)
IS  - 1687-9201 (Print)
IS  - 1687-9201 (Linking)
VI  - 2011
DP  - 2011
TI  - Early posttreatment audiometry underestimates hearing recovery after 
      intratympanic steroid treatment of sudden sensorineural hearing loss.
PG  - 465831
LID - 10.1155/2011/465831 [doi]
LID - 465831
AB  - Objective. To review our experience with intratympanic steroids (ITSs) for the 
      treatment of idiopathic sudden sensorineural hearing loss (ISSNHL), emphasizing 
      the ideal time to perform follow-up audiograms. Methods. Retrospective case 
      review of patients diagnosed with ISSNHL treated with intratympanic 
      methylprednisolone. Injections were repeated weekly with a total of 3 injections. 
      Improvement was defined as an improved pure-tone average >/=20 dB or 
      speech-discrimination score >/=20%. Results. Forty patients met the inclusion 
      criteria with a recovery rate of 45% (18/40). A significantly increased response 
      rate was found in patients having an audiogram >5 weeks after the first dose of 
      ITS (9/13) over those tested </=5 weeks after the first dose of ITS (9/27) (P = 
      0.03). Conclusions. Recovery from ISSNHL after ITS injections occurs more 
      frequently >5 weeks after initiating ITS. This may be due to the natural history 
      of sudden hearing loss or the prolonged effect of steroid in the inner ear.
FAU - Wycherly, Benjamin J
AU  - Wycherly BJ
AD  - Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical 
      Center, 3800 Reservoir Road, NW, Washington, DC 20007, USA.
FAU - Thompkins, Jared J
AU  - Thompkins JJ
FAU - Kim, H Jeffrey
AU  - Kim HJ
LA  - eng
PT  - Journal Article
DEP - 20111128
PL  - United States
TA  - Int J Otolaryngol
JT  - International journal of otolaryngology
JID - 101518366
PMC - PMC3228375
EDAT- 2011/12/14 06:00
MHDA- 2011/12/14 06:01
PMCR- 2011/11/28
CRDT- 2011/12/14 06:00
PHST- 2011/04/24 00:00 [received]
PHST- 2011/09/15 00:00 [accepted]
PHST- 2011/12/14 06:00 [entrez]
PHST- 2011/12/14 06:00 [pubmed]
PHST- 2011/12/14 06:01 [medline]
PHST- 2011/11/28 00:00 [pmc-release]
AID - 10.1155/2011/465831 [doi]
PST - ppublish
SO  - Int J Otolaryngol. 2011;2011:465831. doi: 10.1155/2011/465831. Epub 2011 Nov 28.