PMID- 22167763
OWN - NLM
STAT- MEDLINE
DCOM- 20120427
LR  - 20111214
IS  - 1522-6662 (Electronic)
IS  - 1098-3511 (Linking)
VI  - 14
IP  - 6
DP  - 2011 Dec
TI  - Stroke after coronary bypass surgery is mainly related to diffuse atherosclerotic 
      disease.
PG  - E366-72
LID - 10.1532/HSF98.20111031 [doi]
AB  - OBJECTIVE: This study aims to investigate the risk factors for postoperative 
      stroke and analysis of outcome after coronary bypass surgery with cardiopulmonary 
      bypass. METHODS: Between 1999 and 2008, 3248 consecutive patients who underwent 
      isolated coronary surgery with cardiopulmonary bypass were prospectively enrolled 
      in the study. Demographic and perioperative data were analyzed. Postoperative 
      stroke was defined as severe adverse neurological events including permanent 
      deficits or cerebral lesions with radiological demonstration of cerebral 
      infarction within the first postoperative month. RESULTS: In total, 32 patients 
      (0.9%) were determined with stroke. Univariate risk factors for postoperative 
      stroke were determined as preoperative unstable angina (P = .006), Canadian Class 
      of Angina (CCA) >/= 3 (P = .001), preoperative creatinin level >1.2 mg/dL (P = 
      .001), left main coronary artery disease (P = .04), chronic obstructive lung 
      disease (P = .04), peripheral arterial disease (P < .001), New York Heart 
      Association (NYHA) Class >/= 3 (P = .004), preoperative renal insufficiency (P = 
      .001), age > 65 years (P = .04), preoperative hypothyroidism (P = .02), 
      postoperative low cardiac output state (P < .001), severe coronary artery disease 
      requiring distal anastomosis >/= 4 (P = .05), non-elective operation (P = .02), and 
      body mass index >/= 25 (P = .02). Multivariate analysis revealed peripheral 
      arterial disease (odds ratio [OR], 5.2; 95% confidence interval [CI], 1.9-14.0; P 
      = .001), severe coronary artery disease (OR, 3.1; 95% CI, 1.1-8.5; P = .02), and 
      postoperative low cardiac output state (OR, 5.1; 95% CI, 1.4-18.2; P = .01) as 
      the independent risk factors. CONCLUSIONS: Stroke after coronary bypass surgery 
      with cardiopulmonary bypass is mainly related to diffuse atherosclerotic disease.
FAU - Senay, Sahin
AU  - Senay S
AD  - Department of Cardiovascular Surgery, Acibadem University, Istanbul, Turkey. 
      sahinsenay@gmail.com
FAU - Toraman, Fevzi
AU  - Toraman F
FAU - Akgun, Yasemin
AU  - Akgun Y
FAU - Aydin, Ebuzer
AU  - Aydin E
FAU - Karabulut, Hasan
AU  - Karabulut H
FAU - Alhan, Cem
AU  - Alhan C
FAU - Sarioglu, Tayyar
AU  - Sarioglu T
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Heart Surg Forum
JT  - The heart surgery forum
JID - 100891112
SB  - IM
MH  - Atherosclerosis/*complications/mortality
MH  - Chi-Square Distribution
MH  - *Coronary Artery Bypass
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/*etiology/mortality
MH  - Prospective Studies
MH  - Risk Factors
MH  - Stroke/*etiology/mortality
EDAT- 2011/12/15 06:00
MHDA- 2012/04/28 06:00
CRDT- 2011/12/15 06:00
PHST- 2011/12/15 06:00 [entrez]
PHST- 2011/12/15 06:00 [pubmed]
PHST- 2012/04/28 06:00 [medline]
AID - Y7181T37N055R651 [pii]
AID - 10.1532/HSF98.20111031 [doi]
PST - ppublish
SO  - Heart Surg Forum. 2011 Dec;14(6):E366-72. doi: 10.1532/HSF98.20111031.