PMID- 22170759 OWN - NLM STAT- MEDLINE DCOM- 20120913 LR - 20120418 IS - 1477-0962 (Electronic) IS - 0961-2033 (Linking) VI - 21 IP - 6 DP - 2012 May TI - The last word on the so-called 'Rowell's syndrome'? PG - 577-85 LID - 10.1177/0961203311430513 [doi] AB - To date, 71 patients having the so-called 'Rowell's syndrome' (RS) have been reported in the literature. However, most of them did not show all the clinical and serological features first described by Rowell and co-workers in 1963. Moreover, since then, subacute cutaneous lupus erythematosus (SCLE) has been identified and the diagnostic criteria as well as the clinical features of erythema multiforme (EM) defined. Accordingly several authors have questioned the existence of RS over the past years. In the present paper, the main clinical, histopathological and immunopathological features of both SCLE and EM are described and all of the cases of RS reported in the literature are also reviewed in depth. A real association between discoid LE and EM was present only in a minority of cases and could be considered a mere coincidence. As for other associations, e.g. those between CLE and lichen planus or psoriasis, the coexistence of CLE and EM does not justify the framing of a separate syndrome as suggested by Rowell et al. FAU - Antiga, E AU - Antiga E AD - Department of Medical and Surgical Critical Care, Section of Clinical, Allergo-immunological and Infettivological Dermatology, University of Florence, Florence, Italy. emiliano.antiga@unifi.it FAU - Caproni, M AU - Caproni M FAU - Bonciani, D AU - Bonciani D FAU - Bonciolini, V AU - Bonciolini V FAU - Fabbri, P AU - Fabbri P LA - eng PT - Journal Article PT - Review DEP - 20111214 PL - England TA - Lupus JT - Lupus JID - 9204265 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Child MH - Comorbidity MH - Erythema Multiforme/diagnosis/*epidemiology MH - Female MH - Humans MH - Lichen Planus/diagnosis/epidemiology MH - Lupus Erythematosus, Cutaneous/diagnosis/*epidemiology MH - Lupus Erythematosus, Systemic/diagnosis/*epidemiology MH - Male MH - Middle Aged MH - Psoriasis/diagnosis/epidemiology MH - Syndrome MH - Young Adult EDAT- 2011/12/16 06:00 MHDA- 2012/09/14 06:00 CRDT- 2011/12/16 06:00 PHST- 2011/12/16 06:00 [entrez] PHST- 2011/12/16 06:00 [pubmed] PHST- 2012/09/14 06:00 [medline] AID - 0961203311430513 [pii] AID - 10.1177/0961203311430513 [doi] PST - ppublish SO - Lupus. 2012 May;21(6):577-85. doi: 10.1177/0961203311430513. Epub 2011 Dec 14.