PMID- 22178091 OWN - NLM STAT- MEDLINE DCOM- 20120723 LR - 20130716 IS - 1090-2376 (Electronic) IS - 1053-8100 (Linking) VI - 21 IP - 1 DP - 2012 Mar TI - Altered and asymmetric default mode network activity in a "hypnotic virtuoso": an fMRI and EEG study. PG - 393-400 LID - 10.1016/j.concog.2011.11.006 [doi] AB - Very highly hypnotizable subjects are rare, easily induced, and able to manifest the whole spectrum of hypnotic phenomena, including post-hypnotic amnesia. The aim of this study was to detect and localize by means of quantitative functional MRI and EEG changes in cortical activity during hypnosis induction and deep "pure hypnosis" in a hypnotic "virtuoso" subject. We focused on areas forming the default mode network (DMN), since previous studies found that very highly suggestible subjects in hypnosis showed decreased activity in anterior DMN. During undisturbed hypnosis, our "virtuoso" subject showed not only detectable changes in DMN, but also peculiar activations of non-DMN areas and hemispheric asymmetries of frontal lobe connectivity. Our findings confirm that hypnosis is associated with significant modulation of connectivity and activity which involve the DMN but are not limited to it, depending on the depth of the hypnotic state, the type of mental content and emotional involvement. CI - Copyright (c) 2011 Elsevier Inc. All rights reserved. FAU - Lipari, S AU - Lipari S AD - Department of Radiology, Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy. FAU - Baglio, F AU - Baglio F FAU - Griffanti, L AU - Griffanti L FAU - Mendozzi, L AU - Mendozzi L FAU - Garegnani, M AU - Garegnani M FAU - Motta, A AU - Motta A FAU - Cecconi, P AU - Cecconi P FAU - Pugnetti, L AU - Pugnetti L LA - eng PT - Case Reports PT - Journal Article DEP - 20111216 PL - United States TA - Conscious Cogn JT - Consciousness and cognition JID - 9303140 SB - IM CIN - Conscious Cogn. 2012 Sep;21(3):1575-6. PMID: 22673372 CIN - Conscious Cogn. 2013 Jun;22(2):385-7. PMID: 23416537 MH - *Brain Mapping MH - Electroencephalography MH - Female MH - Humans MH - *Hypnosis MH - Magnetic Resonance Imaging MH - Middle Aged MH - Nerve Net/*physiology EDAT- 2011/12/20 06:00 MHDA- 2012/07/24 06:00 CRDT- 2011/12/20 06:00 PHST- 2011/02/24 00:00 [received] PHST- 2011/11/08 00:00 [revised] PHST- 2011/11/20 00:00 [accepted] PHST- 2011/12/20 06:00 [entrez] PHST- 2011/12/20 06:00 [pubmed] PHST- 2012/07/24 06:00 [medline] AID - S1053-8100(11)00282-0 [pii] AID - 10.1016/j.concog.2011.11.006 [doi] PST - ppublish SO - Conscious Cogn. 2012 Mar;21(1):393-400. doi: 10.1016/j.concog.2011.11.006. Epub 2011 Dec 16.