PMID- 22179034 OWN - NLM STAT- MEDLINE DCOM- 20120501 LR - 20220409 IS - 1879-0844 (Electronic) IS - 1388-9842 (Linking) VI - 14 IP - 1 DP - 2012 Jan TI - The European CRT Survey: 1 year (9-15 months) follow-up results. PG - 61-73 LID - 10.1093/eurjhf/hfr158 [doi] AB - AIMS: The European CRT Survey is a joint initiative of the Heart Failure Association (HFA) and the European Heart Rhythm Association (EHRA) of the European Society of Cardiology evaluating the contemporary implantation practice of cardiac resynchronization therapy (CRT) in Europe. METHODS AND RESULTS: Patients who had a successful CRT implantation were enrolled from 141 centres in 13 countries between November 2008 and June 2009. Baseline demographics, clinical and implantation data were collected, with a follow-up of approximately 1 year (9-15 months). The current report describes clinical outcomes including symptom severity, cardiovascular (CV) hospitalization, and survival. A total of 2438 patients were enrolled, and follow-up data were acquired from 2111 patients (87%). The population included important groups of patients poorly represented in randomized controlled trials, including very elderly patients and those with prior device implantation, atrial fibrillation, and/or QRS duration <120 ms. Investigators reported substantial improvement in New York Heart Association (NYHA) functional class at follow-up. Patient self-assessment indicated that 81% of the patients felt improved, 16% reported no change, and 4% reported deterioration. During follow-up, 207 (10%) patients died, 346 (16%) had a CV hospitalization, and 501 (24%) died or had CV hospitalization. Worse NYHA functional class, atrial fibrillation, ischaemic aetiology, and device type (CRT-P, i.e. CRT alone) were associated with poorer survival. Women had a better outcome, as did patients who had a CRT-D (with an implantable cardioverter defibrillator function) device. CONCLUSIONS: Outcomes including death and hospitalization in this European CRT survey were consistent with results from clinical trials of CRT. At 1 year follow-up, most patients who received a CRT device considered their symptoms improved compared with their pre-implant assessment. Although prospective, this is an observational study of successful CRT implantations, and outcomes in subgroup analyses must be interpreted with appropriate conservatism. FAU - Bogale, Nigussie AU - Bogale N AD - Stavanger University Hospital, Stavanger, Norway. nigussie.bogale@lyse.net FAU - Priori, Silvia AU - Priori S FAU - Cleland, John G F AU - Cleland JG FAU - Brugada, Josep AU - Brugada J FAU - Linde, Cecilia AU - Linde C FAU - Auricchio, Angelo AU - Auricchio A FAU - van Veldhuisen, Dirk J AU - van Veldhuisen DJ FAU - Limbourg, Tobias AU - Limbourg T FAU - Gitt, Anselm AU - Gitt A FAU - Gras, Daniel AU - Gras D FAU - Stellbrink, Christoph AU - Stellbrink C FAU - Gasparini, Maurizio AU - Gasparini M FAU - Metra, Marco AU - Metra M FAU - Derumeaux, Genevieve AU - Derumeaux G FAU - Gadler, Fredrik AU - Gadler F FAU - Buga, Laszlo AU - Buga L FAU - Dickstein, Kenneth AU - Dickstein K CN - Scientific Committee, National Coordinators, and Investigators LA - eng SI - ClinicalTrials.gov/NCT01185392 PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Eur J Heart Fail JT - European journal of heart failure JID - 100887595 SB - IM MH - Aged MH - *Atrial Fibrillation/complications/diagnosis/therapy MH - *Cardiac Resynchronization Therapy/methods/mortality/statistics & numerical data MH - Cardiac Resynchronization Therapy Devices/statistics & numerical data MH - Data Collection MH - Europe MH - Female MH - Follow-Up Studies MH - *Heart Failure/complications/diagnosis/therapy MH - Heart Function Tests/methods MH - Hospitalization MH - Humans MH - Male MH - Middle Aged MH - Multicenter Studies as Topic MH - Outcome and Process Assessment, Health Care MH - Randomized Controlled Trials as Topic MH - Risk Assessment/methods/statistics & numerical data MH - Risk Factors MH - Severity of Illness Index MH - Survival Analysis MH - Treatment Outcome FIR - Dickstein, Kenneth IR - Dickstein K FIR - Priori, Silvia IR - Priori S FIR - Auricchio, Angelo IR - Auricchio A FIR - Bogale, Nigussie IR - Bogale N FIR - Brugada, Josep IR - Brugada J FIR - Cleland, John G F IR - Cleland JG FIR - Derumeaux, Genevieve IR - Derumeaux G FIR - Gitt, Anselm IR - Gitt A FIR - Gras, Daniel IR - Gras D FIR - Komajda, Michel IR - Komajda M FIR - Linde, Cecilia IR - Linde C FIR - Morgan, John IR - Morgan J FIR - van Veldhuisen, Dirk J IR - van Veldhuisen DJ FIR - Fruhwald, Friedrich IR - Fruhwald F FIR - Strohmer, Bernhard IR - Strohmer B FIR - Goethals, Marc IR - Goethals M FIR - Vijgen, Johan IR - Vijgen J FIR - Trochu, Jean Noel IR - Trochu JN FIR - Gras, Daniel IR - Gras D FIR - Kindermann, Michael IR - Kindermann M FIR - Stellbrink, Christoph IR - Stellbrink C FIR - McDonnald, Ken IR - McDonnald K FIR - Keane, David IR - Keane D FIR - Ben Gal, Tuvia IR - Ben Gal T FIR - Glikson, Michael IR - Glikson M FIR - Metra, Marco IR - Metra M FIR - Gasparini, Maurizio IR - Gasparini M FIR - Maass, Alexander IR - Maass A FIR - Jordaens, Luc IR - Jordaens L FIR - Alings, Marco IR - Alings M FIR - Larsen, Alf Inge IR - Larsen AI FIR - Faerestrand, Svein IR - Faerestrand S FIR - Delgado, Juan IR - Delgado J FIR - Mont, Lluis IR - Mont L FIR - Persson, Hans IR - Persson H FIR - Gadler, Fredrik IR - Gadler F FIR - Brunner-La Rocca, Hans Peter IR - Brunner-La Rocca HP FIR - Osswald, Stefan IR - Osswald S FIR - Squire, Ian IR - Squire I FIR - Morgan, John IR - Morgan J EDAT- 2011/12/20 06:00 MHDA- 2012/05/02 06:00 CRDT- 2011/12/20 06:00 PHST- 2011/12/20 06:00 [entrez] PHST- 2011/12/20 06:00 [pubmed] PHST- 2012/05/02 06:00 [medline] AID - hfr158 [pii] AID - 10.1093/eurjhf/hfr158 [doi] PST - ppublish SO - Eur J Heart Fail. 2012 Jan;14(1):61-73. doi: 10.1093/eurjhf/hfr158.