PMID- 22193051
OWN - NLM
STAT- MEDLINE
DCOM- 20120709
LR  - 20131121
IS  - 1364-5528 (Electronic)
IS  - 0003-2654 (Linking)
VI  - 137
IP  - 4
DP  - 2012 Feb 21
TI  - Determination of selected natural hormones and endocrine disrupting compounds in 
      domestic wastewater treatment plants by liquid chromatography electrospray 
      ionization tandem mass spectrometry after solid phase extraction.
PG  - 884-9
LID - 10.1039/c2an15644j [doi]
AB  - A new analytical method for the simultaneous determination of two natural 
      hormones (progesterone and estrone) and two selected endocrine disrupter 
      compounds (EDCs) (diltiazem and carbamazepine (Cbz)) was developed by liquid 
      chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) 
      after pre-concentration with solid phase extraction (SPE). Influent and effluent 
      samples taken from five different wastewater treatment plants throughout Turkey 
      namely Hurma/Antalya, Lara/Antalya, Kemer-1 and Kemer-2 and METU/Ankara were 
      analyzed for their EDCs contents under the optimum conditions. All of the 
      parameters in the pre-concentration step were optimized and the best recoveries 
      for all compounds of interest were achieved at pH 7 (about 100%). Progesterone 
      was not detected in any of the treatment plants while diltiazem was found in all 
      samples with the exception of Lara effluent.
FAU - Muz, Melis
AU  - Muz M
AD  - Middle East Technical University, Department of Environmental Engineering, 06531, 
      Ankara, Turkey.
FAU - Sonmez, M Selcen
AU  - Sonmez MS
FAU - Komesli, Okan Tarik
AU  - Komesli OT
FAU - Bakirdere, Sezgin
AU  - Bakirdere S
FAU - Gokcay, Celal Ferdi
AU  - Gokcay CF
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111223
PL  - England
TA  - Analyst
JT  - The Analyst
JID - 0372652
RN  - 0 (Endocrine Disruptors)
RN  - 0 (Sewage)
RN  - 0 (Water Pollutants, Chemical)
RN  - 2DI9HA706A (Estrone)
RN  - 33CM23913M (Carbamazepine)
RN  - 4G7DS2Q64Y (Progesterone)
RN  - EE92BBP03H (Diltiazem)
SB  - IM
MH  - Carbamazepine/analysis
MH  - Diltiazem/analysis
MH  - Endocrine Disruptors/*analysis
MH  - Environmental Monitoring/*methods
MH  - Estrone/*analysis
MH  - Progesterone/*analysis
MH  - Sewage/*analysis
MH  - Solid Phase Extraction/methods
MH  - Spectrometry, Mass, Electrospray Ionization/methods
MH  - Turkey
MH  - Water Pollutants, Chemical/*analysis/chemistry
EDAT- 2011/12/24 06:00
MHDA- 2012/07/10 06:00
CRDT- 2011/12/24 06:00
PHST- 2011/12/24 06:00 [entrez]
PHST- 2011/12/24 06:00 [pubmed]
PHST- 2012/07/10 06:00 [medline]
AID - 10.1039/c2an15644j [doi]
PST - ppublish
SO  - Analyst. 2012 Feb 21;137(4):884-9. doi: 10.1039/c2an15644j. Epub 2011 Dec 23.