PMID- 22194242
OWN - NLM
STAT- MEDLINE
DCOM- 20120423
LR  - 20120302
IS  - 1097-6817 (Electronic)
IS  - 0194-5998 (Linking)
VI  - 146
IP  - 3
DP  - 2012 Mar
TI  - The necessity of dissection of level IIb in laryngeal squamous cell carcinoma: a 
      clinical study.
PG  - 390-4
LID - 10.1177/0194599811430818 [doi]
AB  - OBJECTIVE: Head and neck squamous cell carcinomas readily metastasize to adjacent 
      cervical lymph nodes. This is seen frequently in laryngeal squamous cell 
      carcinoma (LSCC), and neck dissection may be performed in addition to excision of 
      the primary lesion. The aim of this study was to define the frequency of level 
      IIb metastasis to the lymph nodes in patients who underwent selective neck 
      dissection because of LSCC. STUDY DESIGN AND SETTING: Cross-sectional study with 
      planned data collection in a tertiary referral hospital. SUBJECTS AND METHODS: 
      Eighty-one patients diagnosed with LSCC were accepted into the study. One hundred 
      forty-eight neck dissection specimens were examined histopathologically, and 
      those with level IIb metastasis were identified. The frequency of level IIb 
      metastasis was evaluated in accordance with the primary tumor site, clinical N 
      stage, central tumor presence, and T stage. RESULTS: Forty-seven of 81 patients 
      were clinically N-, and 34 patients were clinically N+. Level IIb metastasis was 
      seen in 5 (6%) of 81 patients, representing 5 of 148 neck dissection specimens. 
      Two of these 5 patients were clinically N+ (6%), and 3 were clinically N- (6%). 
      The relationship between level IIb metastasis and clinical N stage was not 
      statistically significant (P >/= .05). Likewise, no statistically significant 
      relationships between the other parameters and level IIb involvement were found. 
      CONCLUSION: Level IIb nodal involvement is very rare in LSCC. Therefore, the area 
      can generally be preserved in elective neck dissection to lessen morbidity and, 
      specifically, to avoid damaging the function of the spinal accessory nerve.
FAU - Dundar, Riza
AU  - Dundar R
AD  - Department of Otorhinolaryngology and Head and Neck Surgery, Kiziltepe State 
      Hospital, Ministry of Health, Mardin, Turkey.
FAU - Aslan, Hale
AU  - Aslan H
FAU - Ozbay, Can
AU  - Ozbay C
FAU - Basoglu, Sinan
AU  - Basoglu S
FAU - Guvenc, Isil Adadan
AU  - Guvenc IA
FAU - Ogredik, Evren Ay
AU  - Ogredik EA
FAU - Ozturkcan, Sedat
AU  - Ozturkcan S
FAU - Tayfun, Mehmet Ali
AU  - Tayfun MA
FAU - Katilmis, Huseyin
AU  - Katilmis H
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20111222
PL  - England
TA  - Otolaryngol Head Neck Surg
JT  - Otolaryngology--head and neck surgery : official journal of American Academy of 
      Otolaryngology-Head and Neck Surgery
JID - 8508176
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma, Squamous Cell/*secondary
MH  - Combined Modality Therapy
MH  - Cross-Sectional Studies
MH  - Disease-Free Survival
MH  - Female
MH  - Follow-Up Studies
MH  - Frozen Sections
MH  - Humans
MH  - Laryngeal Neoplasms/mortality/*pathology/*surgery
MH  - Laryngectomy/methods/mortality
MH  - Lymph Node Excision/methods/mortality
MH  - Lymphatic Metastasis/*pathology
MH  - Male
MH  - Middle Aged
MH  - Neck Dissection/*methods/mortality/statistics & numerical data
MH  - Neoplasm Invasiveness/pathology
MH  - Neoplasm Staging
MH  - Postoperative Complications/epidemiology/pathology
MH  - Prospective Studies
MH  - Risk Assessment
MH  - Survival Analysis
MH  - Treatment Outcome
EDAT- 2011/12/24 06:00
MHDA- 2012/04/24 06:00
CRDT- 2011/12/24 06:00
PHST- 2011/12/24 06:00 [entrez]
PHST- 2011/12/24 06:00 [pubmed]
PHST- 2012/04/24 06:00 [medline]
AID - 0194599811430818 [pii]
AID - 10.1177/0194599811430818 [doi]
PST - ppublish
SO  - Otolaryngol Head Neck Surg. 2012 Mar;146(3):390-4. doi: 10.1177/0194599811430818. 
      Epub 2011 Dec 22.