PMID- 22201146
OWN - NLM
STAT- MEDLINE
DCOM- 20120214
LR  - 20220408
IS  - 1098-4275 (Electronic)
IS  - 0031-4005 (Linking)
VI  - 129
IP  - 1
DP  - 2012 Jan
TI  - Allergy testing in childhood: using allergen-specific IgE tests.
PG  - 193-7
LID - 10.1542/peds.2011-2382 [doi]
AB  - A variety of triggers can induce common pediatric allergic diseases which include 
      asthma, allergic rhinitis, atopic dermatitis, food allergy, and anaphylaxis. 
      Allergy testing serves to confirm an allergic trigger suspected on the basis of 
      history. Tests for allergen-specific immunoglobulin E (IgE) are performed by in 
      vitro assays or skin tests. The tests are excellent for identifying a sensitized 
      state in which allergen-specific IgE is present, and may identify triggers to be 
      eliminated and help guide immunotherapy treatment. However, a positive test 
      result does not always equate with clinical allergy. Newer enzymatic assays based 
      on anti-IgE antibodies have supplanted the radioallergosorbent test (RAST). This 
      clinical report focuses on allergen-specific IgE testing, emphasizing that the 
      medical history and knowledge of disease characteristics are crucial for rational 
      test selection and interpretation.
FAU - Sicherer, Scott H
AU  - Sicherer SH
FAU - Wood, Robert A
AU  - Wood RA
CN  - American Academy of Pediatrics Section On Allergy And Immunology
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20111226
PL  - United States
TA  - Pediatrics
JT  - Pediatrics
JID - 0376422
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens/*immunology
MH  - Child
MH  - Cross Reactions
MH  - Food Hypersensitivity/diagnosis
MH  - Humans
MH  - Hypersensitivity/*diagnosis
MH  - Immunoglobulin E/*analysis
MH  - Infant
MH  - Respiratory Hypersensitivity/diagnosis
FIR - Sicherer, Scott H
IR  - Sicherer SH
FIR - Abramson, Stuart
IR  - Abramson S
FIR - Chipps, Bradley E
IR  - Chipps BE
FIR - Fleisher, Thomas
IR  - Fleisher T
FIR - Lester, Mitchell R
IR  - Lester MR
FIR - Mahr, Todd A
IR  - Mahr TA
FIR - Matsui, Elizabeth C
IR  - Matsui EC
FIR - Virant, Frank S
IR  - Virant FS
FIR - Williams, Paul V
IR  - Williams PV
EDAT- 2011/12/28 06:00
MHDA- 2012/02/15 06:00
CRDT- 2011/12/28 06:00
PHST- 2011/12/28 06:00 [entrez]
PHST- 2011/12/28 06:00 [pubmed]
PHST- 2012/02/15 06:00 [medline]
AID - peds.2011-2382 [pii]
AID - 10.1542/peds.2011-2382 [doi]
PST - ppublish
SO  - Pediatrics. 2012 Jan;129(1):193-7. doi: 10.1542/peds.2011-2382. Epub 2011 Dec 26.