PMID- 22207571
OWN - NLM
STAT- MEDLINE
DCOM- 20130123
LR  - 20211021
IS  - 1347-4715 (Electronic)
IS  - 1342-078X (Print)
IS  - 1342-078X (Linking)
VI  - 17
IP  - 5
DP  - 2012 Sep
TI  - Characteristics of reactive oxygen metabolites in serum of early teenagers in 
      Japan.
PG  - 364-70
LID - 10.1007/s12199-011-0261-7 [doi]
AB  - OBJECTIVES: The relationship between the incidence of cardiovascular disease and 
      the state of oxidative stress in blood has been studied to some extent. Several 
      lines of evidence underscore the importance of primary prevention of 
      cardiovascular disease beginning in childhood. However, little is known about the 
      current state of oxidative stress in childhood. This study was carried out to 
      determine the current state of the level of reactive oxygen metabolites (ROM) in 
      serum of early teenagers. METHODS: This study enrolled 595 healthy junior high 
      school students from the town of Nanbu located in northern Japan. Oxidative 
      stress was evaluated by measuring the serum level of ROM, and antioxidant 
      capacity was evaluated by measuring the serum level of biological antioxidant 
      potential (BAP). RESULTS: Although the ROM level in female students [308.6 +/- 63.1 
      Carratelli units (U.CARR)] was slightly higher than that in males (299.9 +/- 55.2 
      U.CARR), the difference was not statistically significant. The BAP level in males 
      was significantly higher than that in females. The levels of ROM and BAP detected 
      in males in the first grade were higher than those in the other grades. In 
      females, only first-graders' BAP was higher than that in other grades. 
      CONCLUSIONS: The current study found that the ROM level in males was negatively 
      correlated with grade. These results suggest the presence of factor(s) that 
      increase oxidative stress in Japanese puberty.
FAU - Kogawa, Terumi
AU  - Kogawa T
AD  - Department of Health Promotion, Hirosaki University Graduate School of Health 
      Sciences, Aomori, Japan. t_kogawa@cc.hirosaki-u.ac.jp
FAU - Nishimura, Miya
AU  - Nishimura M
FAU - Kurauchi, Shizuka
AU  - Kurauchi S
FAU - Kashiwakura, Ikuo
AU  - Kashiwakura I
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111230
PL  - Japan
TA  - Environ Health Prev Med
JT  - Environmental health and preventive medicine
JID - 9609642
RN  - 0 (Antioxidants)
RN  - 0 (Reactive Oxygen Species)
SB  - IM
MH  - Adolescent
MH  - Age Factors
MH  - Antioxidants/*metabolism
MH  - Female
MH  - Humans
MH  - Japan
MH  - Male
MH  - Oxidation-Reduction
MH  - *Oxidative Stress
MH  - Photometry
MH  - Reactive Oxygen Species/*blood
MH  - Reference Values
MH  - Sex Factors
PMC - PMC3437360
EDAT- 2011/12/31 06:00
MHDA- 2013/01/24 06:00
PMCR- 2013/09/01
CRDT- 2011/12/31 06:00
PHST- 2011/09/27 00:00 [received]
PHST- 2011/12/12 00:00 [accepted]
PHST- 2011/12/31 06:00 [entrez]
PHST- 2011/12/31 06:00 [pubmed]
PHST- 2013/01/24 06:00 [medline]
PHST- 2013/09/01 00:00 [pmc-release]
AID - 261 [pii]
AID - 10.1007/s12199-011-0261-7 [doi]
PST - ppublish
SO  - Environ Health Prev Med. 2012 Sep;17(5):364-70. doi: 10.1007/s12199-011-0261-7. 
      Epub 2011 Dec 30.