PMID- 22207606
OWN - NLM
STAT- MEDLINE
DCOM- 20131210
LR  - 20220129
IS  - 1530-8022 (Electronic)
IS  - 0885-3282 (Linking)
VI  - 27
IP  - 8
DP  - 2013 May
TI  - Influence of screw holes and gamma sterilization on properties of phosphate glass 
      fiber-reinforced composite bone plates.
PG  - 990-1002
LID - 10.1177/0885328211431855 [doi]
AB  - Polymers prepared from polylactic acid (PLA) have found a multitude of uses as 
      medical devices. For a material that degrades, the main advantage is that an 
      implant would not necessitate a second surgical event for removal. In this study, 
      fibers produced from a quaternary phosphate-based glass (PBG) in the system 
      50P2O5-40CaO-5Na2O-5Fe2O3 were used to reinforce PLA polymer. The purpose of this 
      study was to assess the effect of screw holes in a range of PBG-reinforced PLA 
      composites with varying fiber layup and volume fraction. The flexural properties 
      obtained showed that the strength and modulus values increased with increasing 
      fiber volume fraction; from 96 MPa to 320 MPa for strength and between 4 GPa and 
      24 GPa for modulus. Furthermore, utilizing a larger number of thinner 
      unidirectional (UD) fiber prepreg layers provided a significant increase in 
      mechanical properties, which was attributed to enhanced wet out and thus better 
      fiber dispersion during production. The effect of gamma sterilization via 
      flexural tests showed no statistically significant difference between the 
      sterilized and nonsterilized samples, with the exception of the modulus values 
      for samples with screw holes. Degradation profiles revealed that samples with 
      screw holes degraded faster than those without screw holes due to an increased 
      surface area for the plates with screw holes in PBS up to 30 days. Scanning 
      electron microscope (SEM) analysis revealed fiber pullout before and after 
      degradation. Compared with various fiber impregnation samples, with 25% volume 
      fraction, 8 thinner unidirectional prepreg stacked samples had the shortest fiber 
      pull-out lengths in comparison to the other samples investigated.
FAU - Han, Na
AU  - Han N
AD  - Composites Group, Division of Materials, Mechanics and Structures, Faculty of 
      Engineering, University of Nottingham, Nottingham, UK.
FAU - Ahmed, Ifty
AU  - Ahmed I
FAU - Parsons, Andrew J
AU  - Parsons AJ
FAU - Harper, Lee
AU  - Harper L
FAU - Scotchford, Colin A
AU  - Scotchford CA
FAU - Scammell, Brigitte E
AU  - Scammell BE
FAU - Rudd, Chris D
AU  - Rudd CD
LA  - eng
GR  - HTD 432/DH_/Department of Health/United Kingdom
PT  - Comparative Study
PT  - Journal Article
DEP - 20111229
PL  - England
TA  - J Biomater Appl
JT  - Journal of biomaterials applications
JID - 8813912
RN  - 0 (Bone Substitutes)
RN  - 0 (Phosphates)
RN  - 0 (Polyesters)
RN  - 0 (Polymers)
RN  - 0 (fiberglass)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 459TN2L5F5 (poly(lactide))
SB  - IM
MH  - Biomechanical Phenomena
MH  - *Bone Plates
MH  - Bone Screws
MH  - Bone Substitutes/*chemistry
MH  - Equipment Failure Analysis
MH  - Fracture Fixation, Internal/instrumentation
MH  - Gamma Rays
MH  - Glass/chemistry
MH  - Humans
MH  - Lactic Acid/chemistry
MH  - Materials Testing
MH  - Microscopy, Electron, Scanning
MH  - Phosphates/chemistry
MH  - Polyesters
MH  - Polymers/chemistry
MH  - Prosthesis Failure
MH  - Sterilization/methods
OTO - NOTNLM
OT  - Phosphate glass fiber
OT  - composites
OT  - flexural properties
OT  - gamma sterilization
OT  - screw holes
EDAT- 2011/12/31 06:00
MHDA- 2013/12/16 06:00
CRDT- 2011/12/31 06:00
PHST- 2011/12/31 06:00 [entrez]
PHST- 2011/12/31 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 0885328211431855 [pii]
AID - 10.1177/0885328211431855 [doi]
PST - ppublish
SO  - J Biomater Appl. 2013 May;27(8):990-1002. doi: 10.1177/0885328211431855. Epub 
      2011 Dec 29.