PMID- 22209304
OWN - NLM
STAT- MEDLINE
DCOM- 20120307
LR  - 20191210
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1223
DP  - 2012 Feb 3
TI  - Determination of aqueous fullerene aggregates in water by ultrasound-assisted 
      dispersive liquid-liquid microextraction with liquid chromatography-atmospheric 
      pressure photoionization-tandem mass spectrometry.
PG  - 15-23
LID - 10.1016/j.chroma.2011.12.034 [doi]
AB  - A simple and solvent-minimized method for the determination of three aqueous 
      fullerene aggregates (nC(6)(0), nC(7)(0), and aqueous [6,6]-phenyl C(6)(1) butyric acid 
      methyl ester (nPCBM)) in water samples is described. The method involves the use 
      of ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) 
      coupled liquid chromatography-tandem mass spectrometry with atmospheric pressure 
      photoionization (LC-APPI-MS/MS). The parameters affecting the extraction 
      efficiency of the analytes from water samples were systematically investigated 
      and the conditions optimized. The best extraction conditions involved the rapid 
      injection of a mixture of 1.0 mL of 2-propanol (as a disperser solvent) and 10 muL 
      of benzyl bromide (as an extraction solvent) into 10 mL of an aqueous solution 
      (pH 10.0) containing 1% sodium chloride in a conical bottom glass tube. After 
      ultrasonication for 1.0 min and centrifugation at 5000 pm (10 min), the 
      sedimented phase 5.0 muL was directly injected into the LC-APPI-MS/MS system. The 
      limits of quantification (LOQs) were 150, 60 and 8 ng L(-)(1) for nPCBM, nC(6)(0) and 
      nC(7)(0), respectively. The precision for these analytes, as indicated by relative 
      standard deviations (RSDs), were less than 12% for both intra- and inter-day 
      analysis. Accuracy, expressed as the mean extraction recovery, was between 70 and 
      86%. A standard addition method was used to quantitate three aqueous fullerene 
      aggregates, and the concentrations of these aqueous fullerene aggregates were 
      determined to be in the range from n.d. to 130 ng L(-)(1) in various environmental 
      samples including municipal influent and effluent samples, industrial wastewater 
      samples, and surface water samples.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Chen, Hsin-Chang
AU  - Chen HC
AD  - Department of Chemistry, National Central University, Chung-Li 320, Taiwan.
FAU - Ding, Wang-Hsien
AU  - Ding WH
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111214
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Fullerenes)
RN  - 0 (Water Pollutants)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Fullerenes/analysis/*isolation & purification
MH  - Liquid Phase Microextraction/economics/*methods
MH  - Sensitivity and Specificity
MH  - Tandem Mass Spectrometry/economics/methods
MH  - Ultrasonics/economics/methods
MH  - Water/*analysis
MH  - Water Pollutants/analysis/*isolation & purification
EDAT- 2012/01/03 06:00
MHDA- 2012/03/08 06:00
CRDT- 2012/01/03 06:00
PHST- 2011/07/28 00:00 [received]
PHST- 2011/12/07 00:00 [revised]
PHST- 2011/12/08 00:00 [accepted]
PHST- 2012/01/03 06:00 [entrez]
PHST- 2012/01/03 06:00 [pubmed]
PHST- 2012/03/08 06:00 [medline]
AID - S0021-9673(11)01818-8 [pii]
AID - 10.1016/j.chroma.2011.12.034 [doi]
PST - ppublish
SO  - J Chromatogr A. 2012 Feb 3;1223:15-23. doi: 10.1016/j.chroma.2011.12.034. Epub 
      2011 Dec 14.