PMID- 22209497 OWN - NLM STAT- MEDLINE DCOM- 20140212 LR - 20130527 IS - 1874-1754 (Electronic) IS - 0167-5273 (Linking) VI - 166 IP - 3 DP - 2013 Jul 1 TI - Frequency domain optical coherence tomography for guidance of coronary stenting. PG - 722-8 LID - S0167-5273(11)02147-4 [pii] LID - 10.1016/j.ijcard.2011.11.090 [doi] AB - OBJECTIVE: To evaluate the role of Frequency domain optical coherence tomography (FD-OCT) in guiding stent implantation procedures. METHODS: Dragonfly-imaging catheter was used pre-intervention, after pre-dilatation or at various stages of stent deployment/post-dilatation to assess lesion severity, characteristics and guide stent expansion/apposition. RESULTS: We performed 398 OCT pull-backs in 108 consecutive patients. The 371 pull-backs analysable, had an average length of 35 mm and encompassed 193 lesions (1.8 lesions per patient). Seventy-six percent of patient had AHA-ACC-class B-C lesions. In the pre-intervention group deferral of treatment was decided for 13/68 pullbacks (19.1%), whereas strategies different from conventional predilatation (e.g. thrombectomy, rotablator, cutting-balloon) were decided in 23 cases (33.8%). After full lesion dilatation 96 pullbacks (25.9%, pre-stenting group) were performed, 46 (47.9%) of which suggested proceeding directly with stenting while 50 (52.1%) suggesting further treatment. Out of the 207 pullbacks in post-stenting group, 29 (14%) suggested new stent implantation because of dissection or residual stenosis; 64 (30.9%) suggested further optimization with high pressure/larger-sized balloon. Average number of pull-backs per patient was 3.4 requiring 75.8 +/- 19.3 ml of iopamidol. No major complications were observed. Five cases (4.6%) of contrast-induced nephropathy were reported. CONCLUSIONS: Repeated examinations with FD-OCT can be safely used to guide stent selection and improve stent expansion and apposition. CI - Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved. FAU - Viceconte, Nicola AU - Viceconte N AD - Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, UK. FAU - Chan, Pak Hei AU - Chan PH FAU - Barrero, Eduardo Alegria AU - Barrero EA FAU - Ghilencea, Liviu AU - Ghilencea L FAU - Lindsay, Alistair AU - Lindsay A FAU - Foin, Nicolas AU - Foin N FAU - Di Mario, Carlo AU - Di Mario C LA - eng PT - Journal Article DEP - 20111230 PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Adult MH - Angioplasty, Balloon, Coronary/*methods MH - Coronary Artery Disease/*diagnosis/*surgery MH - Female MH - Humans MH - Male MH - Middle Aged MH - Retrospective Studies MH - Stents MH - Time Factors MH - Tomography, Optical Coherence/*methods MH - Ultrasonography, Interventional/methods EDAT- 2012/01/03 06:00 MHDA- 2014/02/13 06:00 CRDT- 2012/01/03 06:00 PHST- 2011/07/08 00:00 [received] PHST- 2011/10/01 00:00 [revised] PHST- 2011/11/27 00:00 [accepted] PHST- 2012/01/03 06:00 [entrez] PHST- 2012/01/03 06:00 [pubmed] PHST- 2014/02/13 06:00 [medline] AID - S0167-5273(11)02147-4 [pii] AID - 10.1016/j.ijcard.2011.11.090 [doi] PST - ppublish SO - Int J Cardiol. 2013 Jul 1;166(3):722-8. doi: 10.1016/j.ijcard.2011.11.090. Epub 2011 Dec 30.