PMID- 22210739 OWN - NLM STAT- MEDLINE DCOM- 20130322 LR - 20161125 IS - 1940-1574 (Electronic) IS - 0003-3197 (Linking) VI - 63 IP - 8 DP - 2012 Nov TI - The prognostic value of serum gamma glutamyl transferase activity on admission in patients with STEMI undergoing primary PCI. PG - 579-85 LID - 10.1177/0003319711431880 [doi] AB - We assessed the association between serum gamma glutamyl transferase (GGT) activity with postprimary percutaneous coronary intervention (PCI) coronary flow and in-hospital major advanced cardiac events (MACEs) in patients with ST elevation myocardial infarction (STEMI). Patients with STEMI (n = 425; males 78%; mean age 60 +/- 13 years) were enrolled. Patients were divided into 3 GGT tertiles and 2 groups according to thrombolysis in myocardial infarction (TIMI) flow grade. The TIMI flow percentages were similar in the 3 GGT tertiles (32%, 45%, and 42%, respectively, P = .336). Total MACE increased with GGT tertiles (among tertiles, respectively; P < .001). The total MACE was significantly higher in impaired flow group than in normal flow group (23% vs 7%; P < .001). At multivariate analyses, serum GGT activity was an independent predictor of in-hospital MACE (odds ratio [OR] 1.12, 95% confidence interval [CI] 1.01-1.33; P < .001). In conclusion, serum GGT activity is associated with in-hospital MACE in patients with STEMI undergoing primary PCI. FAU - Akpek, Mahmut AU - Akpek M AD - Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey. mahmutapek@yahoo.com FAU - Elcik, Deniz AU - Elcik D FAU - Kalay, Nihat AU - Kalay N FAU - Yarlioglues, Mikail AU - Yarlioglues M FAU - Dogdu, Orhan AU - Dogdu O FAU - Sahin, Omer AU - Sahin O FAU - Ardic, Idris AU - Ardic I FAU - Oguzhan, Abdurrahman AU - Oguzhan A FAU - Ergin, Ali AU - Ergin A FAU - Kaya, Mehmet G AU - Kaya MG LA - eng PT - Journal Article DEP - 20111229 PL - United States TA - Angiology JT - Angiology JID - 0203706 RN - EC 2.3.2.2 (gamma-Glutamyltransferase) SB - IM MH - Coronary Angiography MH - Coronary Vessels/diagnostic imaging MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Myocardial Infarction/*blood/therapy MH - Patient Admission MH - *Percutaneous Coronary Intervention MH - Prognosis MH - Regional Blood Flow MH - Treatment Outcome MH - gamma-Glutamyltransferase/*blood EDAT- 2012/01/03 06:00 MHDA- 2013/03/23 06:00 CRDT- 2012/01/03 06:00 PHST- 2012/01/03 06:00 [entrez] PHST- 2012/01/03 06:00 [pubmed] PHST- 2013/03/23 06:00 [medline] AID - 0003319711431880 [pii] AID - 10.1177/0003319711431880 [doi] PST - ppublish SO - Angiology. 2012 Nov;63(8):579-85. doi: 10.1177/0003319711431880. Epub 2011 Dec 29.