PMID- 2221138
OWN - NLM
STAT- MEDLINE
DCOM- 19901119
LR  - 20171213
IS  - 0002-9513 (Print)
IS  - 0002-9513 (Linking)
VI  - 259
IP  - 4 Pt 2
DP  - 1990 Oct
TI  - Angiotensin and salt appetite of BALB/c mice.
PG  - R729-35
AB  - The influence of systemic or intracerebroventricular (icv) administration of 
      angiotensin II on the intakes of NaCl solution, water, and food was investigated 
      in BALB/c mice. Systemic administration of angiotensin II had little, if any, 
      influence on these ingestive behaviors. On the other hand, icv infusion of 
      angiotensin II at 70 ng/day increased (P less than 0.05) intakes of NaCl solution 
      and water by the third day of infusion. The amount of NaCl ingested daily during 
      the infusion was two to three times body sodium content. The mean daily water 
      intake increased to 40-60% of body weight. The vast increase in NaCl intake was 
      not secondary to a natriuresis caused by the icv infusion of angiotensin II. The 
      results suggest that angiotensin II has a direct effect on neural systems 
      involved in sodium appetite in this species.
FAU - Denton, D A
AU  - Denton DA
AD  - Howard Florey Institute of Experimental Physiology and Medicine, University of 
      Melbourne, Parkville, Victoria, Australia.
FAU - Blair-West, J R
AU  - Blair-West JR
FAU - McBurnie, M
AU  - McBurnie M
FAU - Osborne, P G
AU  - Osborne PG
FAU - Tarjan, E
AU  - Tarjan E
FAU - Williams, R M
AU  - Williams RM
FAU - Weisinger, R S
AU  - Weisinger RS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am J Physiol
JT  - The American journal of physiology
JID - 0370511
RN  - 0 (Angiotensins)
RN  - 11128-99-7 (Angiotensin II)
RN  - 451W47IQ8X (Sodium Chloride)
RN  - 72007-47-7 (crinia-angiotensin)
SB  - IM
MH  - Angiotensin II/pharmacology/*physiology
MH  - Angiotensins/pharmacology
MH  - Animals
MH  - Appetite/*physiology
MH  - Brain/physiology
MH  - Injections, Intraperitoneal
MH  - Injections, Intraventricular
MH  - Injections, Subcutaneous
MH  - Male
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Natriuresis/drug effects
MH  - *Sodium Chloride
EDAT- 1990/10/01 00:00
MHDA- 1990/10/01 00:01
CRDT- 1990/10/01 00:00
PHST- 1990/10/01 00:00 [pubmed]
PHST- 1990/10/01 00:01 [medline]
PHST- 1990/10/01 00:00 [entrez]
AID - 10.1152/ajpregu.1990.259.4.R729 [doi]
PST - ppublish
SO  - Am J Physiol. 1990 Oct;259(4 Pt 2):R729-35. doi: 10.1152/ajpregu.1990.259.4.R729.