PMID- 22213781
OWN - NLM
STAT- MEDLINE
DCOM- 20120813
LR  - 20120410
IS  - 1423-0151 (Electronic)
IS  - 1011-7571 (Linking)
VI  - 21
IP  - 3
DP  - 2012
TI  - Lack of association of mouse mammary tumor virus-like sequences in Iranian breast 
      cancer patients.
PG  - 244-8
LID - 10.1159/000334572 [doi]
AB  - OBJECTIVE: The present study aimed to detect mouse mammary tumor virus 
      (MMTV)-like sequences in Iranian breast cancer patients in the city of Shiraz, 
      located in southwest Iran. SUBJECTS AND METHODS: We searched for two MMTV genetic 
      regions in the peripheral blood leukocytes of 300 women with breast cancer, 300 
      age-matched healthy control subjects, and 50 breast tumor tissues. Two regions of 
      MMTV, 660 bp and 250 bp, were searched by nested polymerase chain reactions. 
      RESULTS: None of the above two regions were detected. There were no differences 
      between the control group and the breast cancer group. CONCLUSION: Our findings 
      did not show any association of MMTV-like sequences with breast cancer 
      development in Iranian patients in Shiraz.
CI  - Copyright (c) 2011 S. Karger AG, Basel.
FAU - Motamedifar, Mohmmad
AU  - Motamedifar M
AD  - Shiraz HIV/Aids Research Center, Shiraz University of Medical Sciences, Shiraz, 
      Iran. motamedm@sums.ac.ir
FAU - Saki, Morteza
AU  - Saki M
FAU - Ghaderi, Abbas
AU  - Ghaderi A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111231
PL  - Switzerland
TA  - Med Princ Pract
JT  - Medical principles and practice : international journal of the Kuwait University, 
      Health Science Centre
JID - 8901334
SB  - IM
MH  - Animals
MH  - Breast Neoplasms/epidemiology/*pathology
MH  - Case-Control Studies
MH  - Cross-Sectional Studies
MH  - Disease Models, Animal
MH  - Female
MH  - Gene Amplification
MH  - Humans
MH  - Iran/epidemiology
MH  - Leukocytes/*pathology
MH  - Mammary Tumor Virus, Mouse/*genetics
MH  - Mice
MH  - Middle Aged
MH  - Polymerase Chain Reaction
MH  - Risk Factors
EDAT- 2012/01/04 06:00
MHDA- 2012/08/14 06:00
CRDT- 2012/01/04 06:00
PHST- 2011/03/23 00:00 [received]
PHST- 2011/10/12 00:00 [accepted]
PHST- 2012/01/04 06:00 [entrez]
PHST- 2012/01/04 06:00 [pubmed]
PHST- 2012/08/14 06:00 [medline]
AID - 000334572 [pii]
AID - 10.1159/000334572 [doi]
PST - ppublish
SO  - Med Princ Pract. 2012;21(3):244-8. doi: 10.1159/000334572. Epub 2011 Dec 31.